> Zinc finger E-box binding homeobox 2 (ZEB2)
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UGID:136304     UniGene Hs.34871     Homo sapiens (human)   ZEB2
Zinc finger E-box binding homeobox 2 (ZEB2)

Human protein-coding gene ZEB2. Represented by 460 ESTs from 189 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 136304 - Hs.34871]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001093437.2 PREDICTED: zinc finger E-box-binding homeobox 2-like isoform 6 M. mulatta 100.0 1253
XP_001158120.1 PREDICTED: zinc finger E-box-binding homeobox 2 isoform 5 P. troglodytes 100.0 1213
NP_055610.1 ZEB2 gene product H. sapiens 100.0 1213
XP_003907501.1 PREDICTED: zinc finger E-box-binding homeobox 2-like P. anubis 99.9 1198
XP_003363286.1 PREDICTED: zinc finger E-box-binding homeobox 2 E. caballus 99.7 1189
XP_004005438.1 PREDICTED: zinc finger E-box-binding homeobox 2 O. aries 99.6 1190
NP_056568.2 Zeb2 gene product M. musculus 98.7 1214
NP_001092145.1 zinc finger E-box binding homeobox 2 X. laevis 92.2 1213
NP_001232895.1 zinc finger E-box-binding homeobox 2 D. rerio 81.5 1218
NP_733402.1 Zn finger homeodomain 1, isoform A D. melanogaster 79.8 84
NP_500424.3 Protein ZAG-1 C. elegans 73.6 129
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_541029.1 PREDICTED: zinc finger E-box-binding homeobox 2 C. lupus familiaris 99.1 1189
XP_003483636.1 PREDICTED: zinc finger E-box-binding homeobox 2-like S. scrofa 99.0 942

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; lung; thymus; muscle; blood; intestine; placenta; pancreas; uterus; eye; connective tissue; vascular; liver; spleen; adrenal gland; pituitary gland; trachea; pineal gland; skin; bone marrow; lymph node; testis; mixed; kidney; embryonic tissue; heart; bone; prostate; stomach; adipose tissue; salivary gland; nerve; ovary; ganglia; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q22.3
UniSTS entry: Chr 2 SHGC-32856 [Map Viewer]
UniSTS entry: Zeb2
UniSTS entry: Chr 2 RH68819
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 1 PMC156606P2
UniSTS entry: Chr 1 PMC156606P3
UniSTS entry: Chr 1 PMC156606P4
UniSTS entry: Chr 1 D8S2278
UniSTS entry: Chr 1 sY3084
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

AB015341.1 Homo sapiens HRIHFB2411 mRNA, partial cds
AK124806.1 Homo sapiens cDNA FLJ42816 fis, clone BRCAN2014881 A
BC070275.1 Homo sapiens cDNA clone IMAGE:30414064, partial cds A
NM_014795.3 Homo sapiens zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 1, mRNA P
AB193096.1 Homo sapiens ZFHX1B mRNA for Smad interacting-protein 1, complete cds, mutation 1395del14ins19 (465fs467X) P
AB193095.1 Homo sapiens ZFHX1B mRNA for Smad interacting-protein 1, complete cds, AluYa5 insertion P
AF161345.1 Homo sapiens HSPC082 mRNA, partial cds
AB056507.1 Homo sapiens ZFHX1B mRNA for Smad interacting protein 1, complete cds P
BC127102.1 Homo sapiens zinc finger E-box binding homeobox 2, mRNA (cDNA clone MGC:150662 IMAGE:40124124), complete cds P
BC127101.1 Homo sapiens zinc finger E-box binding homeobox 2, mRNA (cDNA clone MGC:150661 IMAGE:40124119), complete cds P
AK308445.1 Homo sapiens cDNA, FLJ98393 P
AK308124.1 Homo sapiens cDNA, FLJ98072 P
AK098835.1 Homo sapiens cDNA FLJ25969 fis, clone CBR02250
BC025730.1 Homo sapiens zinc finger E-box binding homeobox 2, mRNA (cDNA clone IMAGE:5203120), with apparent retained intron A
BC025696.1 Homo sapiens zinc finger E-box binding homeobox 2, mRNA (cDNA clone IMAGE:5209578), with apparent retained intron A
AF085983.1 Homo sapiens full length insert cDNA clone YT94E02 A
AK294928.1 Homo sapiens cDNA FLJ55880 complete cds, highly similar to Zinc finger homeobox protein 1b P
NM_001171653.1 Homo sapiens zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 2, mRNA P
BC035706.1 Homo sapiens zinc finger homeobox 1b, mRNA (cDNA clone IMAGE:5575905), partial cds A
BC037975.1 Homo sapiens zinc finger E-box binding homeobox 2, mRNA (cDNA clone IMAGE:5214927), with apparent retained intron PA
NR_033258.1 Homo sapiens zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 3, non-coding RNA A
AB011141.1 Homo sapiens mRNA for KIAA0569 protein, partial cds P

EST sequences (10 of 460) [Show all sequences]

AA969266.1 Clone IMAGE:1560787 mixed 3' read A
R15285.1 Clone IMAGE:29880 brain 5' read
AI040192.1 Clone IMAGE:1659005 embryonic tissue 3' read A
CB045167.1 Clone IMAGE:3218133 intestine 5' read
CB051178.1 Clone IMAGE:3289529 prostate 3' read P
CB051179.1 Clone IMAGE:3289529 prostate 5' read P
BX101266.1 Clone IMAGp998G222036_;_IMAGE:824109 lymph node
BX108751.1 Clone IMAGp998P095586_;_IMAGE:2257016 stomach A
CB144625.1 Clone L16HLK3-22-F11 liver 5' read
T06966.1 Clone HFBEB59 brain P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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