> Proenkephalin (PENK)
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UGID:192372     UniGene Hs.339831     Homo sapiens (human)   PENK Order cDNA clone, Links
Proenkephalin (PENK)

Human protein-coding gene PENK. Represented by 202 ESTs from 45 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 192372 - Hs.339831]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001155627.1 PREDICTED: proenkephalin-A isoform 3 P. troglodytes 100.0 266
NP_001129162.1 PENK gene product H. sapiens 100.0 266
NP_001002927.1 proenkephalin-A precursor M. musculus 87.7 267
NP_001088343.2 proenkephalin preproprotein X. laevis 68.6 254
NP_956377.1 penka gene product D. rerio 46.9 228
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_003902825.1 PREDICTED: proenkephalin-A P. anubis 98.9 266
XP_002808525.1 PREDICTED: LOW QUALITY PROTEIN: proenkephalin-A-like M. mulatta 97.4 266

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; bone; uncharacterized tissue; prostate; muscle; ovary; larynx; pituitary gland; skin; ear; eye; mixed; lung; adipose tissue; mammary gland; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8q23-q24
UniSTS entry: Chr 8 RH46963 [Map Viewer]
UniSTS entry: Chr 8 RH18068 [Map Viewer]
UniSTS entry: Chr 8 PENK
UniSTS entry: Chr 8 PENK
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_006211.3 Homo sapiens proenkephalin (PENK), transcript variant 2, mRNA PA
CR541828.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0632D for gene PENK, proenkephalin; complete cds, without stopcodon P
CR541808.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0631D for gene PENK, proenkephalin; complete cds, incl. stopcodon P
BC107706.1 Homo sapiens proenkephalin, mRNA (cDNA clone IMAGE:6617092), partial cds PA
AK314908.1 Homo sapiens cDNA, FLJ95813, Homo sapiens proenkephalin (PENK), mRNA P
AK309758.1 Homo sapiens cDNA, FLJ99799
BC032505.1 Homo sapiens proenkephalin, mRNA (cDNA clone MGC:45212 IMAGE:5244387), complete cds PA
NM_001135690.1 Homo sapiens proenkephalin (PENK), transcript variant 1, mRNA PA

EST sequences (10 of 202) [Show all sequences]

AI363200.1 Clone IMAGE:2017204 brain 3' read A
AI459701.1 Clone IMAGE:1953303 brain 3' read
AI611304.1 Clone IMAGE:2251269 prostate 3' read A
AI652049.1 Clone IMAGE:2306881 uncharacterized tissue 3' read PA
AI675880.1 Clone IMAGE:2314397 prostate 3' read PA
AI752346.1 Clone NHTBC_cn15b03 bone P
AI752347.1 Clone NHTBC_cn15b03 bone
AI799925.1 Clone IMAGE:2321160 prostate 3' read A
CB267601.1 adipose tissue 5' read
BX281917.1 Clone IMAGp998N2011418_;_IMAGE:5168467 brain P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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