> Farnesyl diphosphate synthase (FDPS)
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UGID:191240     UniGene Hs.335918     Homo sapiens (human)   FDPS Order cDNA clone, Links
Farnesyl diphosphate synthase (FDPS)

Human protein-coding gene FDPS. Represented by 1493 ESTs from 365 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 191240 - Hs.335918]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001160391.1 PREDICTED: farnesyl pyrophosphate synthase isoform 10 P. troglodytes 100.0 418
NP_001129293.1 FDPS gene product H. sapiens 100.0 418
NP_001240680.1 farnesyl pyrophosphate synthase isoform 1 precursor M. musculus 90.0 419
NP_001084626.1 uncharacterized protein LOC414582 X. laevis 80.8 342
NP_001020642.1 fdps gene product D. rerio 76.4 355
XP_001693168.1 farnesyl diphosphate synthase C. reinhardtii 59.4 356
XP_961541.1 farnesyl pyrophosphate synthetase N. crassa 59.1 339
NP_012368.1 Erg20p S. cerevisiae 56.7 343
NP_477380.1 farnesyl pyrophosphate synthase D. melanogaster 55.3 340
NP_193452.1 farnesyl diphosphate synthase 2 A. thaliana 55.3 339
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
XP_003892831.1 PREDICTED: farnesyl pyrophosphate synthase isoform 3 P. anubis 98.6 418
XP_003365053.1 PREDICTED: farnesyl pyrophosphate synthase E. caballus 93.8 419

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; liver; lung; skin; pancreas; placenta; uncharacterized tissue; embryonic tissue; ovary; lymph; eye; intestine; uterus; mixed; prostate; kidney; muscle; blood; testis; mammary gland; stomach; pharynx; adrenal gland; spinal cord; cervix; amniotic fluid; salivary gland; larynx; trachea; epididymis; tonsil; heart; ear; ascites; bone; bone marrow; connective tissue; lymph node; mouth; esophagus; spleen; thyroid; thymus; vascular; bladder; umbilical cord; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q22
UniSTS entry: D15S513
UniSTS entry: Chr 1 D15S1171
UniSTS entry: Chr 1 RH68206
UniSTS entry: Chr 1 SHGC-2651
UniSTS entry: Chr 1 D15S1477
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

M29863.1 Human farnesyl pyrophosphate synthetase mRNA (hpt807), 3' end P
D14697.1 Homo sapiens KIAA1293 mRNA, partial cds P
NM_002004.3 Homo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 1, mRNA PA
J05262.1 Human farnesyl pyrophosphate synthetase mRNA, complete cds PA
BC010004.2 Homo sapiens farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase), mRNA (cDNA clone MGC:15352 IMAGE:4132071), complete cds PA
AK291084.1 Homo sapiens cDNA FLJ76177 complete cds, highly similar to Homo sapiens farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) (FDPS), mRNA PA
NM_001135822.1 Homo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 3, mRNA PA
NM_001135821.1 Homo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 2, mRNA PA
NM_001242825.1 Homo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 5, mRNA PA
NM_001242824.1 Homo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 4, mRNA PA

EST sequences (10 of 1493) [Show all sequences]

AA902979.1 Clone IMAGE:1516823 uncharacterized tissue 3' read
AA999963.1 Clone IMAGE:1636516 kidney 3' read PA
AI033671.1 Clone IMAGE:1647601 parathyroid 3' read PA
AI050803.1 Clone IMAGE:1637102 kidney 3' read PA
AI052344.1 Clone IMAGE:1676003 mixed 3' read PA
AA948374.1 Clone IMAGE:1589417 kidney 3' read PA
AI066793.1 Clone IMAGE:1637576 uncharacterized tissue 3' read PA
AI074630.1 Clone IMAGE:1662690 mixed 3' read PA
AI094131.1 Clone IMAGE:1688648 mixed 3' read PA
AI128887.1 Clone IMAGE:1663082 skin 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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