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UGID:130737     UniGene Hs.334     Homo sapiens (human)   ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5 (ARHGEF5)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_005426.2 rho guanine nucleotide exchange factor 5 H. sapiens 100.0 1596
NP_598435.1 Rho guanine nucleotide exchange factor (GEF) 5 M. musculus 79.5 1580
NP_001128552.1 Rho guanine nucleotide exchange factor 19 X. laevis 54.5 578

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; kidney; skin; ovary; mammary gland; placenta; pancreas; heart; uncharacterized tissue; eye; brain; lung; uterus; prostate; stomach; embryonic tissue; amniotic fluid; bone marrow; adrenal gland; mouth; bladder; epididymis; thyroid; cervix; ascites; mixed; connective tissue; parathyroid; bone; testis; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q33-q35
UniSTS entry: Chr 7 RH80813
UniSTS entry: Chr 7 TIM1
UniSTS entry: Chr 7 RH103260
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BX649178.1 Homo sapiens mRNA; cDNA DKFZp686O18190 (from clone DKFZp686O18190) PA
AK123596.1 Homo sapiens cDNA FLJ41602 fis, clone CTONG3000084, highly similar to PROBABLE GUANINE NUCLEOTIDE REGULATORY PROTEIN TIM P
NM_005435.3 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 5 (ARHGEF5), mRNA PA
AK160365.1 Homo sapiens mRNA for FLJ00261 protein P
CR749203.1 Homo sapiens mRNA; cDNA DKFZp686N1969 (from clone DKFZp686N1969) PA
BC010046.2 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 5, mRNA (cDNA clone IMAGE:3636857), complete cds PA
BC011839.2 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 5, mRNA (cDNA clone IMAGE:3953394), complete cds PA
BC014555.2 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 5, mRNA (cDNA clone IMAGE:3614104), complete cds PA
U02082.1 Human guanine nucleotide regulatory protein (tim1) mRNA, complete cds P
AK090570.1 Homo sapiens cDNA FLJ33251 fis, clone ASTRO2005242, highly similar to Rho guanine nucleotide exchange factor 5 P
BC136661.1 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 5, mRNA (cDNA clone MGC:168274 IMAGE:9020651), complete cds P

EST sequences (10 of 91) [Show all sequences]

AI027395.1 Clone IMAGE:1650135 parathyroid 3' read A
CB051710.1 Clone IMAGE:3289849 uncharacterized tissue 5' read A
AI159969.1 Clone IMAGE:1706462 heart 3' read A
AI185784.1 Clone IMAGE:1741891 lung 3' read A
AI285171.1 Clone IMAGE:1874346 intestine 3' read A
AI304394.1 Clone IMAGE:1912834 intestine 3' read A
CB216819.1 Clone IMAGE:5938548 uterus 5' read P
AI435375.1 Clone IMAGE:2124728 mixed 3' read A
AI628094.1 Clone IMAGE:2285781 kidney 3' read
AI654460.1 Clone IMAGE:2216143 ovary 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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