> Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) (TLE2)
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UGID:189373     UniGene Hs.332173     Homo sapiens (human)   TLE2 Order cDNA clone, Links
Transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) (TLE2)

Human protein-coding gene TLE2. Represented by 219 ESTs from 115 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 189373 - Hs.332173]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003251.2 TLE2 gene product H. sapiens 100.0 742
XP_003914684.1 PREDICTED: transducin-like enhancer protein 2 P. anubis 99.7 742
NP_062699.1 Tle2 gene product M. musculus 93.1 766
NP_001084260.1 transducin-like enhancer of split 4 X. laevis 82.7 767
NP_571855.1 gro1 gene product D. rerio 80.4 770
NP_001189294.1 groucho, isoform G D. melanogaster 75.5 727
NP_491932.1 Protein UNC-37 C. elegans 63.1 351
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_512979.3 PREDICTED: transducin-like enhancer protein 2 isoform 8 P. troglodytes 99.1 746
XP_003354045.1 PREDICTED: transducin-like enhancer protein 2-like S. scrofa 99.0 675

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; prostate; eye; liver; bladder; bone; heart; connective tissue; uterus; mammary gland; placenta; testis; pharynx; uncharacterized tissue; intestine; pancreas; mixed; kidney; stomach; embryonic tissue; muscle; skin; mouth; thymus; parathyroid; ascites; spleen; nerve; tonsil; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
UniSTS entry: Chr 19 STS-AA037755
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AK123183.1 Homo sapiens cDNA FLJ41188 fis, clone BRACE2044304, highly similar to TRANSDUCIN-LIKE ENHANCER PROTEIN 2 P
NM_003260.4 Homo sapiens transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) (TLE2), transcript variant 1, mRNA PA
M99436.1 Human transducin-like enhancer protein (TLE2) mRNA, complete cds P
BC017364.2 Homo sapiens transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila), mRNA (cDNA clone MGC:10518 IMAGE:3925626), complete cds PA
AK308608.1 Homo sapiens cDNA, FLJ98649 P
AK308137.1 Homo sapiens cDNA, FLJ98085 PA
AK312285.1 Homo sapiens cDNA, FLJ92587 P
AK293482.1 Homo sapiens cDNA FLJ61693 complete cds, highly similar to Transducin-like enhancer protein 2 P
AK293407.1 Homo sapiens cDNA FLJ59666 complete cds, highly similar to Transducin-like enhancer protein 2 P
AK303102.1 Homo sapiens cDNA FLJ53117 complete cds, highly similar to Transducin-like enhancer protein 2 P
NM_001144762.1 Homo sapiens transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) (TLE2), transcript variant 3, mRNA PA
NM_001144761.1 Homo sapiens transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) (TLE2), transcript variant 2, mRNA PA

EST sequences (10 of 219) [Show all sequences]

AA961098.1 Clone IMAGE:1569802 lung 3' read A
AA975013.1 Clone IMAGE:1560983 mixed 3' read A
AI127832.1 Clone IMAGE:1711730 uterus 3' read PA
R24598.1 Clone IMAGE:131786 placenta 5' read
BX105520.1 Clone IMAGp998E071162_;_IMAGE:488430 uterus P
AI208059.1 Clone IMAGE:1837597 testis 3' read A
AI276234.1 Clone IMAGE:1878262 mixed 3' read A
AI337092.1 Clone IMAGE:2009555 uncharacterized tissue 3' read A
AI364365.1 Clone IMAGE:2018066 brain 3' read A
AI420901.1 Clone IMAGE:2095170 prostate 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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