Alanyl-tRNA synthetase (AARS)

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UGID:184601 UniGene Hs.315137 Homo sapiens (human) AARS

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Alanyl-tRNA synthetase (AARS)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001169474.1	PREDICTED: alanyl-tRNA synthetase isoform 1	P. troglodytes	100.0	967
NP_001596.2	alanyl-tRNA synthetase	H. sapiens	100.0	967
NP_666329.2	alanyl-tRNA synthetase	M. musculus	97.8	967
NP_001121342.1	hypothetical protein LOC100158432	X. laevis	90.1	967
NP_001037775.1	alanyl-tRNA synthetase	D. rerio	88.1	967
NP_523511.2	Alanyl-tRNA synthetase, isoform A	D. melanogaster	73.3	963
NP_491281.1	Alanyl tRNA Synthetase family member (ars-2)	C. elegans	68.9	964
XP_001694980.1	predicted protein	C. reinhardtii	65.9	749
NP_014980.1	Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog; Ala1p	S. cerevisiae	64.0	955
NP_175439.2	ALATS (ALANYL-TRNA SYNTHETASE); ATP binding / alanine-tRNA ligase/ ligase, forming aminoacyl-tRNA and related compounds / nucleic acid binding / nucleotide binding	A. thaliana	63.7	946
XP_965697.2	alanyl-tRNA synthetase	N. crassa	60.2	959

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; intestine; lymph; embryonic tissue; uncharacterized tissue; lung; eye; skin; uterus; placenta; prostate; pancreas; mammary gland; cervix; bone marrow; mixed; thyroid; testis; kidney; liver; mouth; esophagus; stomach; pharynx; larynx; ovary; vascular; muscle; epididymis; tonsil; salivary gland; ascites; connective tissue; blood; bone; lymph node; pituitary gland; adrenal gland; heart; spleen; bladder; adipose tissue; nerve; thymus; ganglia

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	16
Map position:	16q22
UniSTS entry:	Chr 16	RH65736
UniSTS entry:	Chr 16	A002L29
UniSTS entry:	Chr 16	RH66606
UniSTS entry:	Chr 16	D16S2972
UniSTS entry:	Chr 16	(n/a)
UniSTS entry:		RH78762

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_001605.2	Homo sapiens alanyl-tRNA synthetase (AARS), mRNA	P
AK222824.1	Homo sapiens mRNA for alanyl-tRNA synthetase variant, clone: HEP06614	PA
D32050.1	Homo sapiens mRNA for alanyl-tRNA synthetase, complete cds	P
AK225116.1	Homo sapiens mRNA for alanyl-tRNA synthetase variant, clone: CBL01544	PA
BC011451.1	Homo sapiens alanyl-tRNA synthetase, mRNA (cDNA clone MGC:9334 IMAGE:3450606), complete cds	PA
AK307782.1	Homo sapiens cDNA, FLJ97730	P
AK299098.1	Homo sapiens cDNA FLJ61339 complete cds, highly similar to Alanyl-tRNA synthetase (EC 6.1.1.7)	P

EST sequences (10 of 901) [Show all sequences]

R17064.1	Clone IMAGE:129785	mixed	5' read	P
R17065.1	Clone IMAGE:129785	mixed	3' read	A
AI028785.1	Clone IMAGE:1645228	testis	3' read
AI092677.1	Clone IMAGE:1693067	heart	3' read	P
AA923316.1	Clone IMAGE:1526281	mixed	3' read
AI168659.1	Clone IMAGE:1661646	mixed	3' read	A
CB162495.1	Clone L17N670205n1-24-E09	liver	5' read	P
AI269687.1	Clone IMAGE:1998264	brain	3' read	A
AI356029.1	Clone IMAGE:2016777	brain	3' read	A
T07996.1	Clone HIBAA33	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria