> Serine peptidase inhibitor, Kunitz type, 2 (SPINT2)
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UGID:135932     UniGene Hs.31439     Homo sapiens (human)   SPINT2
Serine peptidase inhibitor, Kunitz type, 2 (SPINT2)

Human protein-coding gene SPINT2. Represented by 1310 ESTs from 333 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 135932 - Hs.31439]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_066925.1 SPINT2 gene product H. sapiens 100.0 251
NP_035594.1 Spint2 gene product M. musculus 73.4 251
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_001106508.1 PREDICTED: kunitz-type protease inhibitor 2-like isoform 1 M. mulatta 98.0 251
XP_003915513.1 PREDICTED: kunitz-type protease inhibitor 2 isoform 1 P. anubis 98.0 251

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; ovary; placenta; intestine; embryonic tissue; brain; uterus; prostate; lung; stomach; mixed; testis; uncharacterized tissue; mammary gland; eye; kidney; ascites; lymph node; thymus; bladder; trachea; skin; blood; bone marrow; esophagus; pituitary gland; amniotic fluid; liver; thyroid; heart; parathyroid; salivary gland; mouth; cervix; connective tissue; vascular; pharynx; lymph; adrenal gland; larynx; bone; nerve; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.1
UniSTS entry: Chr 19 A007F08
UniSTS entry: Chr 19 WI-14931 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

CR407604.1 Homo sapiens full open reading frame cDNA clone RZPDo834G037D for gene SPINT2, serine protease inhibitor, Kunitz type, 2 complete cds, without stopcodon P
BT020117.1 Homo sapiens serine protease inhibitor, Kunitz type, 2 mRNA, complete cds P
BT020116.1 Homo sapiens serine protease inhibitor, Kunitz type, 2 mRNA, complete cds P
BT020115.1 Homo sapiens serine protease inhibitor, Kunitz type, 2 mRNA, complete cds P
NM_021102.3 Homo sapiens serine peptidase inhibitor, Kunitz type, 2 (SPINT2), transcript variant a, mRNA PA
BC001668.2 Homo sapiens serine peptidase inhibitor, Kunitz type, 2, mRNA (cDNA clone MGC:2021 IMAGE:2959462), complete cds PA
BC007705.2 Homo sapiens serine peptidase inhibitor, Kunitz type, 2, mRNA (cDNA clone MGC:11327 IMAGE:3952243), complete cds PA
BC012868.2 Homo sapiens serine peptidase inhibitor, Kunitz type, 2, mRNA (cDNA clone MGC:9154 IMAGE:3857277), complete cds PA
BC011955.1 Homo sapiens serine peptidase inhibitor, Kunitz type, 2, mRNA (cDNA clone MGC:17172 IMAGE:3857238), complete cds PA
BC011951.1 Homo sapiens serine peptidase inhibitor, Kunitz type, 2, mRNA (cDNA clone MGC:17171 IMAGE:3856970), complete cds PA
AK291532.1 Homo sapiens cDNA FLJ76861 complete cds, highly similar to Homo sapiens serine peptidase inhibitor, Kunitz type, 2 (SPINT2), mRNA P
AK297154.1 Homo sapiens cDNA FLJ52992 complete cds, highly similar to Kunitz-type protease inhibitor 2 precursor PA
Z36849.1 H.sapiens (xs97) mRNA, 349bp
NM_001166103.1 Homo sapiens serine peptidase inhibitor, Kunitz type, 2 (SPINT2), transcript variant b, mRNA PA
U78095.1 Homo sapiens placental bikunin mRNA, complete cds PA
AF027205.1 Homo sapiens Kunitz-type protease inhibitor (kop) mRNA, complete cds P
AB006534.1 Homo sapiens mRNA for hepatocyte growth factor activator inhibitor type 2, complete cds P

EST sequences (10 of 1310) [Show all sequences]

AA866041.1 Clone IMAGE:1470294 uncharacterized tissue 3' read A
AA975281.1 Clone IMAGE:1588460 uncharacterized tissue 3' read A
AI003490.1 Clone IMAGE:1699088 kidney 3' read A
AI022639.1 Clone IMAGE:1655459 mixed 3' read A
AI034105.1 Clone IMAGE:1646297 parathyroid 3' read
AI034115.1 Clone IMAGE:1646324 parathyroid 3' read A
AI041481.1 Clone IMAGE:1648192 parathyroid 3' read
AI052011.1 Clone IMAGE:1667249 parathyroid 3' read A
AI057583.1 Clone IMAGE:1667428 parathyroid 3' read
AI066478.1 Clone IMAGE:1679284 skin 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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