Cytidine monophosphate N-acetylneuraminic acid synthetase (CMAS)

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UGID:183701 UniGene Hs.311346 Homo sapiens (human) CMAS

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Cytidine monophosphate N-acetylneuraminic acid synthetase (CMAS)

Human protein-coding gene CMAS. Represented by 430 ESTs from 195 cDNA libraries. Corresponds to reference sequence NM_018686.4. [UniGene 183701 - Hs.311346]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_520794.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: N-acylneuraminate cytidylyltransferase isoform 2	P. troglodytes	100.0	433
NP_061156.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CMAS gene product	H. sapiens	100.0	433
XP_001099303.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: n-acylneuraminate cytidylyltransferase	M. mulatta	99.8	433
XP_003906150.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: N-acylneuraminate cytidylyltransferase	P. anubis	99.8	433
NP_034038.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	N-acylneuraminate cytidylyltransferase	M. musculus	97.9	431
NP_001035342.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	N-acylneuraminate cytidylyltransferase	D. rerio	68.4	415
Other hits (2 of 23) [Show all]		Species	Id(%)	Len(aa)
XP_534866.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: N-acylneuraminate cytidylyltransferase isoform 2	C. lupus familiaris	99.3	433
XP_002712764.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cytidine monophospho-N-acetylneuraminic acid synthetase	O. cuniculus	98.6	433

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; testis; intestine; embryonic tissue; uncharacterized tissue; placenta; kidney; blood; connective tissue; amniotic fluid; bladder; cervix; lymph; ascites; mixed; ear; ovary; prostate; bone; liver; pancreas; eye; lung; pharynx; muscle; mouth; uterus; skin; stomach; lymph node; mammary gland; pituitary gland; heart; esophagus; thyroid; bone marrow; ganglia

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	12
Map position:	12p12.1
UniSTS entry:	Chr 12	STS-W85899

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AK124990.1	Homo sapiens cDNA FLJ43000 fis, clone BRTHA2012555, moderately similar to Homo sapiens cytidine monophosphate N-acetylneuraminic acid synthetase (CMAS)
NM_018686.4	Homo sapiens cytidine monophosphate N-acetylneuraminic acid synthetase (CMAS), mRNA	PA
AF271388.1	Homo sapiens CMP-N-acetylneuraminic acid synthase mRNA, complete cds	P
AK222981.1	Homo sapiens mRNA for cytidine 5'-monophosphate N-acetylneuraminic acid synthetase variant, clone: HSI02232	PA
AK022927.1	Homo sapiens cDNA FLJ12865 fis, clone NT2RP2003643, moderately similar to Mus musculus mRNA for CMP-N-acetylneuraminic acid synthetase	P
BC016609.1	Homo sapiens cytidine monophosphate N-acetylneuraminic acid synthetase, mRNA (cDNA clone MGC:5424 IMAGE:3448277), complete cds	PA
AL832975.1	Homo sapiens mRNA; cDNA DKFZp666I142 (from clone DKFZp666I142)	PA
AF397212.1	Homo sapiens cytidine monophospho-sialic acid synthase mRNA, complete cds	P

EST sequences (10 of 430) [Show all sequences]

AA993125.1	Clone IMAGE:1620160	testis	3' read	A
AI022308.1	Clone IMAGE:1652253	mixed	3' read	A
AI040142.1	Clone IMAGE:1658958	embryonic tissue	3' read
AI127768.1	Clone IMAGE:1711223	uterus	3' read	A
AI241914.1	Clone IMAGE:1977571	brain	3' read	A
AI262457.1	Clone IMAGE:1871502	intestine	3' read	A
AI269785.1	Clone IMAGE:1871814	intestine	3' read	A
AI271969.1	Clone IMAGE:1865549	kidney	3' read	A
CB134115.1	Clone L14ChoiCK0-5-F11	liver	5' read	PA
CB134681.1	Clone L14ChoiCK0-15-H02	liver	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria