> Inhibitor of Bruton agammaglobulinemia tyrosine kinase (IBTK)
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UGID:182367     UniGene Hs.306425     Homo sapiens (human)   IBTK Order cDNA clone, Links
Inhibitor of Bruton agammaglobulinemia tyrosine kinase (IBTK)

Human protein-coding gene IBTK. Represented by 278 ESTs from 156 cDNA libraries. Corresponds to reference sequence NM_015525.2. [UniGene 182367 - Hs.306425]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056340.2 IBTK gene product H. sapiens 100.0 1352
XP_001148806.1 PREDICTED: inhibitor of Bruton tyrosine kinase isoform 3 P. troglodytes 99.7 1352
NP_001074751.1 Ibtk gene product M. musculus 90.3 1351
NP_001084927.1 inhibitor of Bruton tyrosine kinase X. laevis 72.5 1338
XP_003200174.1 PREDICTED: inhibitor of Bruton tyrosine kinase-like D. rerio 66.7 1325
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_003897893.1 PREDICTED: inhibitor of Bruton tyrosine kinase-like P. anubis 98.6 1351
XP_002803869.1 PREDICTED: inhibitor of Bruton tyrosine kinase-like M. mulatta 98.3 1297

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; embryonic tissue; liver; uncharacterized tissue; placenta; pituitary gland; eye; lung; uterus; cervix; kidney; mammary gland; pancreas; pharynx; ovary; ear; skin; intestine; thymus; heart; adrenal gland; testis; lymph node; muscle; adipose tissue; stomach; bladder; prostate; lymph; trachea; larynx; bone; connective tissue; mouth; ascites; nerve; bone marrow; parathyroid; vascular
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q14.1
UniSTS entry: Chr 6 D6S1882 [Map Viewer]
UniSTS entry: Chr 6 D6S1109E
UniSTS entry: Chr 6 A002S42
UniSTS entry: Chr 6 D6S1188E
UniSTS entry: Chr 6 IBTK__6437
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

BC042171.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone IMAGE:5455086), partial cds PA
AL050018.1 Homo sapiens mRNA; cDNA DKFZp564B116 (from clone DKFZp564B116); partial cds PA
AK123460.1 Homo sapiens cDNA FLJ41466 fis, clone BRSTN2017771, moderately similar to Homo sapiens BTK-binding protein mRNA P
AB037838.2 Homo sapiens mRNA for KIAA1417 protein, partial cds P
BC092410.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone IMAGE:6194327) PA
DQ005635.1 Homo sapiens inhibitor of Bruton's tyrosine kinase-gamma mRNA, complete cds P
DQ005633.1 Homo sapiens inhibitor of Bruton's tyrosine kinase-alpha mRNA, complete cds P
DQ005634.1 Homo sapiens inhibitor of Bruton's tyrosine kinase-beta mRNA, complete cds P
AF235049.1 Homo sapiens putative BTK-binding protein mRNA, complete cds PA
BC113698.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone MGC:142258 IMAGE:8322750), complete cds P
BC113696.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone MGC:142256 IMAGE:8322748), complete cds P
AJ420593.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 684359 PA
AJ420588.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 2049662 PA
BC112929.1 Homo sapiens cDNA clone IMAGE:6500006, containing frame-shift errors PA
BC027490.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone IMAGE:3924074), partial cds PA
BC027483.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone IMAGE:4388667), partial cds PA
BC012551.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone IMAGE:4274392), with apparent retained intron P
BC143748.1 Homo sapiens cDNA clone IMAGE:9052262 P
BC143736.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone MGC:177267 IMAGE:9052250), complete cds P
BC143745.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone MGC:177276 IMAGE:9052259), complete cds P
BC035860.1 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone IMAGE:3924738), partial cds PA
BC038244.2 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase, mRNA (cDNA clone IMAGE:5240896), partial cds PA
NM_015525.2 Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase (IBTK), mRNA P

EST sequences (10 of 278) [Show all sequences]

AA970524.1 Clone IMAGE:1579313 mixed 3' read A
AA971694.1 Clone IMAGE:1584554 lung 3' read A
R17235.1 Clone IMAGE:31947 brain 5' read
AI026976.1 Clone IMAGE:1649363 parathyroid 3' read A
AI080197.1 Clone IMAGE:1677343 mixed 3' read A
AI125582.1 Clone IMAGE:1736725 testis 3' read A
AI128207.1 Clone IMAGE:1712800 uterus 3' read A
AI140662.1 Clone IMAGE:1739723 lung 3' read A
AI140997.1 Clone IMAGE:1671006 uncharacterized tissue 3' read A
CB044948.1 Clone IMAGE:3218068 intestine 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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