> Destrin (actin depolymerizing factor) (DSTN)
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UGID:182027     UniGene Hs.304192     Homo sapiens (human)   DSTN Order cDNA clone, Links
Destrin (actin depolymerizing factor) (DSTN)

Human protein-coding gene DSTN. Represented by 948 ESTs from 322 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 182027 - Hs.304192]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001182421.1 destrin (actin depolymerizing factor) M. mulatta 100.0 164
XP_003914332.1 PREDICTED: destrin-like P. anubis 100.0 164
XP_514526.3 PREDICTED: destrin isoform 3 P. troglodytes 100.0 164
NP_006861.1 DSTN gene product H. sapiens 100.0 164
NP_001004031.1 DSTN gene product S. scrofa 100.0 164
NP_001015586.1 DSTN gene product B. taurus 100.0 164
XP_002711006.1 PREDICTED: destrin O. cuniculus 100.0 164
XP_001915675.2 PREDICTED: destrin-like E. caballus 100.0 147
XP_004014333.1 PREDICTED: destrin O. aries 100.0 147
NP_062745.1 Dstn gene product M. musculus 97.6 164
NP_001088171.1 cofilin-2 X. laevis 72.9 166
NP_991263.1 cfl2 gene product D. rerio 71.7 165
Other hits (2 of 13) [Show all]SpeciesId(%)Len(aa)
XP_001374193.2 PREDICTED: destrin-like M. domestica 99.4 177
XP_534337.3 PREDICTED: destrin C. lupus familiaris 99.4 172

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; embryonic tissue; placenta; lung; intestine; eye; prostate; uncharacterized tissue; skin; stomach; mixed; heart; bladder; pancreas; mammary gland; testis; connective tissue; kidney; liver; bone; lymph node; spleen; esophagus; cervix; parathyroid; bone marrow; ganglia; amniotic fluid; ovary; trachea; adrenal gland; umbilical cord; pituitary gland; lymph; muscle; olfactory mucosa; ascites; adipose tissue; thyroid; nerve; vascular; mouth; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20p12.1
UniSTS entry: Chr 20 RH17904 [Map Viewer]
UniSTS entry: Chr 20 STS-R82498 [Map Viewer]
UniSTS entry: Chr 20 D20S1015 [Map Viewer]
UniSTS entry: Chr 20 SHGC-58414
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BX647319.1 Homo sapiens mRNA; cDNA DKFZp686O20275 (from clone DKFZp686O20275) PA
NM_006870.3 Homo sapiens destrin (actin depolymerizing factor) (DSTN), transcript variant 1, mRNA P
CR457042.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0515D for gene DSTN, destrin (actin depolymerizing factor); complete cds, incl. stopcodon P
CR541956.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0334D for gene DSTN, destrin (actin depolymerizing factor); complete cds, without stopcodon P
NM_001011546.1 Homo sapiens destrin (actin depolymerizing factor) (DSTN), transcript variant 2, mRNA P
BC009477.2 Homo sapiens destrin (actin depolymerizing factor), mRNA (cDNA clone MGC:15087 IMAGE:3938287), complete cds PA
AK308562.1 Homo sapiens cDNA, FLJ98603 P
AK312645.1 Homo sapiens cDNA, FLJ93031, Homo sapiens destrin (actin depolymerizing factor) (DSTN), mRNA P
AK302338.1 Homo sapiens cDNA FLJ52030 complete cds, highly similar to Destrin P
AK315994.1 Homo sapiens cDNA, FLJ78893 complete cds, highly similar to Destrin PA
S65738.1 actin depolymerizing factor [human, fetal brain, mRNA, 1452 nt] P

EST sequences (10 of 948) [Show all sequences]

AA976257.1 Clone IMAGE:1567725 lung 3' read
AA991788.1 Clone IMAGE:1623870 embryonic tissue 3' read A
AI082739.1 Clone IMAGE:1652880 mixed 3' read PA
R23606.1 Clone IMAGE:132119 placenta 5' read
CB049537.1 Clone IMAGE:3271398 prostate 3' read PA
CB049538.1 Clone IMAGE:3271398 prostate 5' read PA
CB049712.1 Clone IMAGE:3271445 prostate 3' read A
BX103679.1 Clone IMAGp998N16228_;_IMAGE:149199 placenta
AI214168.1 Clone IMAGE:1956924 brain 3' read P
AI218248.1 Clone IMAGE:1845522 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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