> Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10)
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UGID:135782     UniGene Hs.30385     Homo sapiens (human)   MLLT10 Links
Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10)

Human protein-coding gene MLLT10. Represented by 258 ESTs from 141 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 135782 - Hs.30385]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001182555.1 MLLT10 gene product H. sapiens 100.0 1067
XP_001097577.2 PREDICTED: protein AF-10-like M. mulatta 99.6 980
XP_003903502.1 PREDICTED: LOW QUALITY PROTEIN: protein AF-10 P. anubis 99.5 1069
NP_001239489.1 Mllt10 gene product M. musculus 95.7 1067
XP_003201338.1 PREDICTED: protein AF-10 D. rerio 83.9 342
NP_731132.1 alhambra, isoform D D. melanogaster 81.0 190
NP_001088071.1 uncharacterized protein LOC494767 X. laevis 77.4 962
NP_498943.2 Protein ZFP-1, isoform a C. elegans 61.2 188
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003312528.2 PREDICTED: LOW QUALITY PROTEIN: protein AF-10 P. troglodytes 98.8 1124
XP_002717449.1 PREDICTED: myeloid/lymphoid or mixed-lineage leukemia translocated to, 10 O. cuniculus 98.1 1052

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; uncharacterized tissue; embryonic tissue; lung; mixed; placenta; uterus; vascular; blood; spleen; larynx; trachea; thyroid; eye; thymus; muscle; prostate; mammary gland; bone; mouth; skin; kidney; pancreas; liver; pharynx; bladder; connective tissue; intestine; ovary; lymph node; stomach; esophagus; ascites; lymph; nerve; heart; ear
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10p12
UniSTS entry: Chr 10 RH102414
UniSTS entry: Chr 10 RH47336
UniSTS entry: Chr 10 SHGC-34521 [Map Viewer]
UniSTS entry: Chr 10 D10S2369
UniSTS entry: Chr 10 STS-U13948
UniSTS entry: Chr 10 MLLT10_1942
UniSTS entry: Chr 1 D1S1423
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 1 D8S2278
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (29)

AF060927.1 Homo sapiens type I AF10/CALM fusion protein (AF10/CALM) mRNA, partial cds
AF060929.1 Homo sapiens type III AF10/CALM fusion protein (AF10/CALM) mRNA, partial cds
AF060935.1 Homo sapiens type II AF10 protein (AF10) mRNA, partial cds
AF060937.1 Homo sapiens type IV AF10 protein (AF10) mRNA, partial cds A
AF060938.1 Homo sapiens type V AF10 protein (AF10) mRNA, partial cds P
BC052798.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, mRNA (cDNA clone IMAGE:5808940), with apparent retained intron PA
BX648210.1 Homo sapiens mRNA; cDNA DKFZp779J0967 (from clone DKFZp779J0967) PA
BX640774.1 Homo sapiens mRNA; cDNA DKFZp686E10210 (from clone DKFZp686E10210) PA
AK126642.1 Homo sapiens cDNA FLJ44684 fis, clone BRACE3010862
NM_004641.3 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10), transcript variant 1, mRNA PA
BC065376.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, mRNA (cDNA clone IMAGE:6671384) PA
AL137295.1 Homo sapiens mRNA; cDNA DKFZp434M2216 (from clone DKFZp434M2216) A
BC080577.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, mRNA (cDNA clone IMAGE:6597328), complete cds PA
AY598745.1 Homo sapiens AF10 (AF10) mRNA, complete cds P
AB209755.1 Homo sapiens mRNA for myeloid/lymphoid or mixed-lineage leukemia translocated to, 10 isoform a variant protein P
BC094844.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, mRNA (cDNA clone IMAGE:6574007), with apparent retained intron PA
BC129946.1 Homo sapiens cDNA clone IMAGE:40124317 P
AK310803.1 Homo sapiens cDNA, FLJ17845 P
AK301213.1 Homo sapiens cDNA FLJ61176 complete cds, highly similar to Protein AF-10 P
BC032532.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10, mRNA (cDNA clone IMAGE:5526778), with apparent retained intron PA
AF060936.1 Homo sapiens type III AF10 protein (AF10) mRNA, partial cds A
AF060934.1 Homo sapiens type I AF10 protein (AF10) mRNA, partial cds P
AF060932.1 Homo sapiens type II CALM/AF10 fusion protein (CALM/AF10) mRNA, partial cds
AF272385.1 Homo sapiens clone 1552r2 MLL/AF-10 fusion protein mRNA, partial cds
NM_001195630.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10), transcript variant 5, mRNA P
NM_001195628.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10), transcript variant 6, mRNA P
NM_001195627.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10), transcript variant 4, mRNA P
NM_001195626.1 Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10), transcript variant 3, mRNA P
U13948.1 Human zinc finger/leucine zipper protein (AF10) mRNA, complete cds P

EST sequences (10 of 258) [Show all sequences]

AA983713.1 Clone IMAGE:1557601 lung 3' read A
AI004069.1 Clone IMAGE:1619915 testis 3' read
T06113.1 Clone HFBDO62 brain P
AI147420.1 Clone IMAGE:1839628 testis 5' read P
BX097328.1 Clone IMAGp998I23461_;_IMAGE:229726 mixed P
BX109927.1 Clone IMAGp998E1189_;_IMAGE:112114 mixed
AI252855.1 Clone IMAGE:1984951 ovary 3' read
CB145334.1 Clone L16HLK3-19-H04 liver 5' read
CB163179.1 Clone L17N670205n1-21-D08 liver 5' read P
CB116339.1 Clone L10ChoCK0-5-C11 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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