> Gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3)
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UGID:181429     UniGene Hs.302352     Homo sapiens (human)   GABRB3 Order cDNA clone, Links
Gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3)

Human protein-coding gene GABRB3. Represented by 253 ESTs from 91 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 181429 - Hs.302352]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001109118.1 PREDICTED: gamma-aminobutyric acid receptor subunit beta-3 isoform 4 M. mulatta 100.0 472
XP_003900724.1 PREDICTED: gamma-aminobutyric acid receptor subunit beta-3 isoform 1 P. anubis 100.0 472
XP_003314618.1 PREDICTED: gamma-aminobutyric acid receptor subunit beta-3 isoform 1 P. troglodytes 100.0 472
NP_068712.1 GABRB3 gene product H. sapiens 100.0 472
NP_032097.1 Gabrb3 gene product M. musculus 98.9 472
XP_695300.3 PREDICTED: gamma-aminobutyric acid receptor subunit beta-3-like isoform 2 D. rerio 91.7 470
NP_499661.2 Protein GAB-1 C. elegans 58.9 292
NP_996469.1 Ligand-gated chloride channel homolog 3 D. melanogaster 57.9 487
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
NP_001092850.1 GABRB3 gene product B. taurus 99.2 471
NP_058761.1 Gabrb3 gene product R. norvegicus 98.7 472

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; uncharacterized tissue; eye; embryonic tissue; pancreas; testis; kidney; larynx; pituitary gland; blood; mixed; cervix; uterus; placenta; connective tissue; nerve; bone; muscle; liver
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q12
UniSTS entry: Chr 15 RH78433
UniSTS entry: Chr 15 STS-R43452
UniSTS entry: Chr 15 RH11160
UniSTS entry: Chr 15 GABRB3_1630
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_000814.5 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 1, mRNA P
M82919.1 Human gamma amino butyric acid (GABAA) receptor beta-3 subunit mRNA, complete cds P
NM_021912.4 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 2, mRNA P
BC010641.1 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3, mRNA (cDNA clone MGC:9051 IMAGE:3871111), complete cds PA
AK056018.1 Homo sapiens cDNA FLJ31456 fis, clone NT2NE2001176
AK315311.1 Homo sapiens cDNA, FLJ96343, highly similar to Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 2, mRNA P
AK095011.1 Homo sapiens cDNA FLJ37692 fis, clone BRHIP2014747
AK302822.1 Homo sapiens cDNA FLJ52810 complete cds, highly similar to Gamma-aminobutyric-acid receptor beta-3 subunit precursor P
AK295167.1 Homo sapiens cDNA FLJ53990 complete cds, highly similar to Gamma-aminobutyric-acid receptor beta-3 subunit precursor P
NM_001191321.1 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 4, mRNA P
NM_001191320.1 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 3, mRNA P

EST sequences (10 of 253) [Show all sequences]

R15880.1 Clone IMAGE:53022 brain 3' read A
AA987326.1 Clone IMAGE:1602400 lung 3' read
R17962.1 Clone IMAGE:32381 brain 5' read
T26992.1 Clone LLAB087C07 brain 5' read
R19959.1 Clone IMAGE:34880 brain 5' read
R24801.1 Clone IMAGE:35449 brain 5' read
BX089338.1 Clone IMAGp998F03159_;_IMAGE:34880 brain A
AI206318.1 Clone IMAGE:1941538 uncharacterized tissue 3' read P
AI208093.1 Clone IMAGE:1838735 testis 3' read
AI216196.1 Clone IMAGE:1884453 lung 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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