> Dual specificity phosphatase 6 (DUSP6)
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UGID:180786     UniGene Hs.298654     Homo sapiens (human)   DUSP6 Order cDNA clone, Links
Dual specificity phosphatase 6 (DUSP6)

Human protein-coding gene DUSP6. Represented by 325 ESTs from 167 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 180786 - Hs.298654]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001101478.1 PREDICTED: dual specificity protein phosphatase 6-like M. mulatta 100.0 380
XP_003906984.1 PREDICTED: dual specificity protein phosphatase 6 P. anubis 100.0 380
XP_001165821.1 PREDICTED: dual specificity protein phosphatase 6 isoform 1 P. troglodytes 100.0 380
NP_001937.2 DUSP6 gene product H. sapiens 100.0 380
XP_852241.1 PREDICTED: dual specificity protein phosphatase 6 isoform 2 C. lupus familiaris 100.0 380
NP_001254771.1 dual specificity protein phosphatase 6 S. scrofa 100.0 380
XP_001492049.2 PREDICTED: dual specificity protein phosphatase 6 isoform 1 E. caballus 99.7 380
NP_001039660.1 DUSP6 gene product B. taurus 99.7 380
XP_002711425.1 PREDICTED: dual specificity phosphatase 6 O. cuniculus 99.7 380
NP_080544.1 Dusp6 gene product M. musculus 99.5 380
NP_001184196.1 uncharacterized protein LOC100505429 X. laevis 99.5 380
NP_919361.1 dusp6 gene product D. rerio 90.6 381
NP_730385.1 Mitogen-activated protein kinase phosphatase 3, isoform A D. melanogaster 56.4 188
NP_501053.2 Protein LIP-1 C. elegans 51.7 149
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
NP_446335.1 Dusp6 gene product R. norvegicus 99.5 380
XP_004006292.1 PREDICTED: dual specificity protein phosphatase 6 isoform 1 O. aries 99.2 365

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; mixed; placenta; embryonic tissue; pancreas; kidney; skin; prostate; bladder; bone marrow; eye; testis; stomach; intestine; thyroid; bone; blood; liver; uncharacterized tissue; mammary gland; uterus; ovary; vascular; lymph node; trachea; adrenal gland; larynx; ascites; pharynx; heart; adipose tissue; ear; connective tissue; nerve; umbilical cord; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q22-q23
UniSTS entry: Chr 12 WI-18566 [Map Viewer]
UniSTS entry: Chr 12 D12S1400 [Map Viewer]
UniSTS entry: Chr 12 WI-14395 [Map Viewer]
UniSTS entry: Chr 12 DUSP6_594
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AB013602.1 Homo sapiens mRNA for DUSP6-ALT, complete cds P
AB013382.1 Homo sapiens mRNA for DUSP6, complete cds P
BT006895.1 Homo sapiens dual specificity phosphatase 6 mRNA, complete cds P
NM_001946.2 Homo sapiens dual specificity phosphatase 6 (DUSP6), transcript variant 1, mRNA PA
AK222882.1 Homo sapiens mRNA for dual specificity phosphatase 6 isoform b variant, clone: HRC00358 P
NM_022652.2 Homo sapiens dual specificity phosphatase 6 (DUSP6), transcript variant 2, mRNA PA
BC003562.1 Homo sapiens dual specificity phosphatase 6, mRNA (cDNA clone MGC:1954 IMAGE:3547162), complete cds PA
BC005047.1 Homo sapiens dual specificity phosphatase 6, mRNA (cDNA clone MGC:12852 IMAGE:3954486), complete cds PA
BC003143.1 Homo sapiens dual specificity phosphatase 6, mRNA (cDNA clone MGC:3789 IMAGE:2906126), complete cds PA
X93920.1 H.sapiens mRNA for protein-tyrosine-phosphatase (tissue type: foreskin) P
AK091753.1 Homo sapiens cDNA FLJ34434 fis, clone HLUNG2000950, highly similar to DUAL SPECIFICITY PROTEIN PHOSPHATASE 6 (EC 3.1.3.48) P
AB451393.1 Homo sapiens DUSP6 mRNA for dual specificity phosphatase 6 isoform a, partial cds, clone: FLJ08085AAAF P
AB451265.1 Homo sapiens DUSP6 mRNA for dual specificity phosphatase 6 isoform a, complete cds, clone: FLJ08085AAAN P
BC037236.1 Homo sapiens dual specificity phosphatase 6, mRNA (cDNA clone MGC:35368 IMAGE:5183133), complete cds PA

EST sequences (10 of 325) [Show all sequences]

AA973395.1 Clone IMAGE:1569002 lung 3' read A
AA976980.1 Clone IMAGE:1587515 uncharacterized tissue 3' read A
AA902518.1 Clone IMAGE:1502476 kidney 3' read A
AI092872.1 Clone IMAGE:1692776 heart 3' read
AI085452.1 Clone IMAGE:1653590 mixed 3' read
AI167965.1 Clone IMAGE:1565679 mixed 3' read A
AI185315.1 Clone IMAGE:1741079 lung 3' read
AI192556.1 Clone IMAGE:1743946 lung 3' read
AI251112.1 Clone IMAGE:2004755 pancreas 3' read A
CB112645.1 Clone L5HLK1-14-H03 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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