> Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (MMP9)
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UGID:180531     UniGene Hs.297413     Homo sapiens (human)   MMP9
Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (MMP9)

Human protein-coding gene MMP9. Represented by 1023 ESTs from 125 cDNA libraries. EST representation biased toward neonate. Corresponds to reference sequence NM_004994.2. [UniGene 180531 - Hs.297413]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004985.2 MMP9 gene product H. sapiens 100.0 706
XP_003317021.1 PREDICTED: matrix metalloproteinase-9 isoform 1 P. troglodytes 99.9 698
NP_038627.1 Mmp9 gene product M. musculus 81.5 729
NP_001091305.1 matrix metalloproteinase-9TH precursor X. laevis 69.5 676
NP_998288.1 mmp9 gene product D. rerio 68.5 672
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_003904714.1 PREDICTED: LOW QUALITY PROTEIN: matrix metalloproteinase-9 P. anubis 96.6 706
XP_001104871.1 PREDICTED: matrix metalloproteinase-9 M. mulatta 96.3 706

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; blood; pharynx; thymus; spleen; embryonic tissue; connective tissue; cervix; brain; stomach; mouth; intestine; trachea; tonsil; eye; testis; prostate; bone; lymph node; lung; pancreas; mixed; mammary gland; esophagus; uterus; ovary; liver; bone marrow; adrenal gland; kidney
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q11.2-q13.1
UniSTS entry: Chr 20 RH11668
UniSTS entry: Chr 20 PMC97903P1
UniSTS entry: Chr 20 WI-7659 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_004994.2 Homo sapiens matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (MMP9), mRNA PA
J05070.1 Human type IV collagenase mRNA, complete cds P
BC006093.1 Homo sapiens matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase), mRNA (cDNA clone MGC:12688 IMAGE:4054882), complete cds PA
AK311648.1 Homo sapiens cDNA, FLJ18690 P
AK313137.1 Homo sapiens cDNA, FLJ93627, highly similar to Homo sapiens matrix metalloproteinase 9 (gelatinase B, 92kDagelatinase, 92kDa type IV collagenase) (MMP9), mRNA P
AK316145.1 Homo sapiens cDNA, FLJ79044 complete cds, highly similar to Matrix metalloproteinase-9 precursor (EC 3.4.24.35) PA
AK303080.1 Homo sapiens cDNA FLJ51166 complete cds, highly similar to Matrix metalloproteinase-9 precursor (EC 3.4.24.35) PA
AK302530.1 Homo sapiens cDNA FLJ52524 complete cds, moderately similar to Matrix metalloproteinase-9 precursor (EC3.4.24.35) PA
AK301446.1 Homo sapiens cDNA FLJ51120 complete cds, highly similar to Matrix metalloproteinase-9 precursor (EC 3.4.24.35) PA
AK298246.1 Homo sapiens cDNA FLJ51036 complete cds, highly similar to Matrix metalloproteinase-9 precursor (EC3.4.24.35) PA
HQ874462.1 Homo sapiens matrix metalloproteinase-9 mRNA, partial cds

EST sequences (10 of 1023) [Show all sequences]

AA983506.1 Clone IMAGE:1598365 uncharacterized tissue 3' read A
AA991884.1 Clone IMAGE:1610559 uncharacterized tissue 3' read PA
AA902643.1 Clone IMAGE:1519368 uncharacterized tissue 3' read A
AI023784.1 Clone IMAGE:1655716 mixed 3' read
AI075104.1 Clone IMAGE:1632721 uncharacterized tissue 3' read A
CB045397.1 Clone IMAGE:3218243 intestine 3' read A
CB045398.1 Clone IMAGE:3218243 intestine 5' read P
BX101214.1 Clone IMAGp998O0470_;_IMAGE:22040 brain A
AI267909.1 Clone IMAGE:1909404 lung 3' read A
AI268673.1 Clone IMAGE:1911676 lung 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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