> Calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2)
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UGID:180497     UniGene Hs.297343     Homo sapiens (human)   CAMKK2 Order cDNA clone, Links
Calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2)

Human protein-coding gene CAMKK2. Represented by 719 ESTs from 235 cDNA libraries. Corresponds to 9 reference sequences (different isoforms). [UniGene 180497 - Hs.297343]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006540.3 CAMKK2 gene product H. sapiens 100.0 587
XP_003952384.1 PREDICTED: calcium/calmodulin-dependent protein kinase kinase 2 P. troglodytes 100.0 386
XP_001094017.1 PREDICTED: calcium/calmodulin-dependent protein kinase kinase 2 isoform 12 M. mulatta 99.7 587
XP_003907328.1 PREDICTED: calcium/calmodulin-dependent protein kinase kinase 2 isoform 1 P. anubis 99.7 587
NP_001186605.1 Camkk2 gene product M. musculus 97.8 587
NP_001082316.1 calcium/calmodulin-dependent protein kinase kinase 1, alpha X. laevis 75.2 444
NP_001014361.1 camkk1 gene product D. rerio 74.5 423
NP_001021152.1 Protein CKK-1, isoform a C. elegans 63.2 378
NP_001036632.1 CG17698, isoform A D. melanogaster 61.7 345
XP_962989.2 hypothetical protein NCU06177 N. crassa 51.1 309
XP_001691565.1 calcium/calmodulin dependent protein kinase kinase 2 C. reinhardtii 48.4 159
NP_200863.2 geminivirus rep interacting kinase 2 A. thaliana 45.9 183
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_002719787.1 PREDICTED: calcium/calmodulin-dependent protein kinase kinase 2 beta isoform 1 O. cuniculus 98.3 582
XP_001915634.2 PREDICTED: LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase kinase 2-like E. caballus 98.3 577

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; prostate; uterus; mixed; blood; lung; mammary gland; kidney; pancreas; intestine; embryonic tissue; ovary; placenta; eye; testis; adrenal gland; heart; esophagus; skin; spleen; lymph; pharynx; mouth; bone marrow; thymus; larynx; cervix; connective tissue; lymph node; liver; stomach; ganglia; bone; ascites; adipose tissue; parathyroid; nerve; umbilical cord; vascular
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24.2
UniSTS entry: Chr 12 RH11188
UniSTS entry: Chr 12 RH11255
UniSTS entry: Chr 12 SGC32416
UniSTS entry: Chr 12 D12S1241E
UniSTS entry: Chr 12 WI-15135 [Map Viewer]
UniSTS entry: Chr 12 WI-19738 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (28)

AF091074.1 Homo sapiens clone 307 unknown mRNA, complete sequence PA
AB018330.2 Homo sapiens mRNA for KIAA0787 protein, partial cds P
AF101264.1 Homo sapiens Ca2+/calmodulin-dependent kinase kinase mRNA, complete cds PA
NM_006549.3 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 1, mRNA PA
AK024748.1 Homo sapiens cDNA: FLJ21095 fis, clone CAS03846 PA
BC000318.2 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta, mRNA (cDNA clone IMAGE:2821696), partial cds PA
AF287631.1 Homo sapiens calcium/calmodulin-dependent protein kinase kinase b2 mRNA, complete cds PA
AF287630.1 Homo sapiens calcium/calmodulin-dependent protein kinase kinase b1 mRNA, complete cds PA
AF321388.1 Homo sapiens CaMKK beta 1 isoform mRNA, complete cds PA
AF321387.1 Homo sapiens CaMKK beta 1 isoform mRNA, complete cds PA
AF321386.1 Homo sapiens CaMKK beta 1 isoform mRNA, complete cds PA
AF321385.1 Homo sapiens CaMKK beta 2 isoform mRNA, complete cds PA
AK292072.1 Homo sapiens cDNA FLJ75891 complete cds, highly similar to Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 2, mRNA P
AK311473.1 Homo sapiens cDNA, FLJ18515
BC026060.2 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta, mRNA (cDNA clone MGC:15254 IMAGE:3842706), complete cds PA
AL834322.1 Homo sapiens mRNA; cDNA DKFZp761L24121 (from clone DKFZp761L24121) PA
AK300865.1 Homo sapiens cDNA FLJ53477 complete cds, highly similar to Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) P
AF425668.1 Homo sapiens CAMKK beta protein (CAMKK2) mRNA, partial cds
AB081337.1 Homo sapiens Camkk beta-3x mRNA for Ca2+/calmodulin-dependent protein kinase kinase beta-3x, complete cds P
AB081336.1 Homo sapiens Camkk beta-3 mRNA for Ca2+/calmodulin-dependent protein kinase kinase beta-3, complete cds P
NM_153499.2 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 2, mRNA PA
NM_001270486.1 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 9, mRNA PA
NM_001270485.1 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 8, mRNA PA
NM_172226.2 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 7, mRNA PA
NM_172216.1 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 3, mRNA PA
NM_172215.2 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 6, mRNA PA
NM_172214.2 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 5, mRNA PA
NM_153500.1 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 2, beta (CAMKK2), transcript variant 4, mRNA PA

EST sequences (10 of 719) [Show all sequences]

R14195.1 Clone IMAGE:28489 brain 5' read
AA991174.1 Clone IMAGE:1607823 mammary gland 3' read A
AA995381.1 Clone IMAGE:1601575 lung 3' read
AI026833.1 Clone IMAGE:1645692 testis 3' read A
R19104.1 Clone IMAGE:32992 brain 5' read
R19148.1 Clone IMAGE:33325 brain 5' read
AA922204.1 Clone IMAGE:1544074 mixed 3' read
R19743.1 Clone IMAGE:34938 brain 5' read
AI081729.1 Clone IMAGE:1653255 mixed 3' read
CB044691.1 Clone IMAGE:3217801 intestine 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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