> Iron-sulfur cluster assembly 2 homolog (S. cerevisiae) (ISCA2)
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UGID:178972     UniGene Hs.291079     Homo sapiens (human)   ISCA2 Order cDNA clone, Links
Iron-sulfur cluster assembly 2 homolog (S. cerevisiae) (ISCA2)

Human protein-coding gene ISCA2. Represented by 129 ESTs from 87 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 178972 - Hs.291079]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001143075.2 PREDICTED: iron-sulfur cluster assembly 2 homolog, mitochondrial P. troglodytes 100.0 153
NP_919255.2 ISCA2 gene product H. sapiens 100.0 153
NP_083139.1 Isca2 gene product M. musculus 95.5 153
XP_001922511.1 PREDICTED: iron-sulfur cluster assembly 2 homolog, mitochondrial isoform 1 D. rerio 68.2 128
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_001094302.1 PREDICTED: iron-sulfur cluster assembly 2 homolog, mitochondrial M. mulatta 99.3 153
XP_003902102.1 PREDICTED: iron-sulfur cluster assembly 2 homolog, mitochondrial P. anubis 99.3 153

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uterus; liver; embryonic tissue; prostate; kidney; uncharacterized tissue; pancreas; lung; eye; placenta; stomach; mammary gland; intestine; heart; blood; mouth; testis; lymph; bone marrow; ovary; ear; bone; connective tissue; bladder; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q24.3
UniSTS entry: Chr 14 RH65075
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

BX248252.1 human full-length cDNA clone CS0DF015YC15 of Fetal brain of Homo sapiens (human) P
NM_194279.3 Homo sapiens iron-sulfur cluster assembly 2 homolog (S. cerevisiae) (ISCA2), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA P
BC015771.1 Homo sapiens iron-sulfur cluster assembly 2 homolog (S. cerevisiae), mRNA (cDNA clone MGC:23248 IMAGE:4849790), complete cds PA
AK290728.1 Homo sapiens cDNA FLJ77080 complete cds, highly similar to Homo sapiens HESB like domain containing 1, mRNA P
BC032893.2 Homo sapiens iron-sulfur cluster assembly 2 homolog (S. cerevisiae), mRNA (cDNA clone MGC:43081 IMAGE:5259721), complete cds PA
NM_001272007.1 Homo sapiens iron-sulfur cluster assembly 2 homolog (S. cerevisiae) (ISCA2), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA

EST sequences (10 of 129) [Show all sequences]

AI018142.1 Clone IMAGE:1626338 mixed 3' read
AI080185.1 Clone IMAGE:1677342 mixed 3' read A
AI127494.1 Clone IMAGE:1708277 heart 3' read
AI146474.1 Clone IMAGE:1707657 heart 3' read PA
BX114918.1 Clone IMAGp998L141945_;_IMAGE:789277 embryonic tissue P
AI218065.1 Clone IMAGE:1846118 mixed 3' read
CB159533.1 Clone L18POOL1n1-39-H05 liver 5' read P
CB138061.1 Clone L5HLK1-39-B01 liver 5' read
CB125490.1 Clone L5HLK1s1-26-H07 liver 5' read P
CB139486.1 Clone L15CKK1-17-B01 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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