> Damage-specific DNA binding protein 1, 127kDa (DDB1)
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UGID:178865     UniGene Hs.290758     Homo sapiens (human)   DDB1 Order cDNA clone, Links
Damage-specific DNA binding protein 1, 127kDa (DDB1)

Human protein-coding gene DDB1. Represented by 1837 ESTs from 513 cDNA libraries. Corresponds to reference sequence NM_001923.4. [UniGene 178865 - Hs.290758]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056550.1 Ddb1 gene product M. musculus 100.0 1139
XP_002725831.1 PREDICTED: DNA damage-binding protein 1 R. norvegicus 100.0 1139
XP_003909786.1 PREDICTED: DNA damage-binding protein 1 P. anubis 100.0 1139
NP_001914.3 DDB1 gene product H. sapiens 100.0 1139
XP_533275.2 PREDICTED: DNA damage-binding protein 1 C. lupus familiaris 100.0 1139
XP_001502072.1 PREDICTED: DNA damage-binding protein 1 E. caballus 100.0 1139
XP_003122699.1 PREDICTED: DNA damage-binding protein 1-like isoform 1 S. scrofa 100.0 1139
NP_001073731.1 DDB1 gene product B. taurus 100.0 1139
XP_004019630.1 PREDICTED: DNA damage-binding protein 1 O. aries 100.0 1139
XP_002721069.1 PREDICTED: damage-specific DNA binding protein 1 O. cuniculus 100.0 1139
XP_001082958.2 PREDICTED: DNA damage-binding protein 1 M. mulatta 100.0 1091
XP_508472.4 PREDICTED: DNA damage-binding protein 1 P. troglodytes 99.9 1094
NP_001083624.1 DNA damage-binding protein 1 X. laevis 97.2 1139
NP_956920.1 ddb1 gene product D. rerio 94.9 896
NP_650257.1 piccolo D. melanogaster 69.7 1139
NP_192451.1 DNA damage-binding protein 1a A. thaliana 63.1 1085
NP_502299.1 Protein DDB-1 C. elegans 50.7 838
XP_001702494.1 UV-damaged DNA binding complex subunit 1 protein C. reinhardtii 50.2 1047
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_002191856.1 PREDICTED: DNA damage-binding protein 1 T. guttata 99.4 1139
XP_003431248.1 PREDICTED: DNA damage-binding protein 1-like O. anatinus 99.3 1032

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; placenta; embryonic tissue; lung; eye; uncharacterized tissue; intestine; uterus; prostate; skin; kidney; mammary gland; mixed; lymph; mouth; thymus; pancreas; ovary; esophagus; thyroid; trachea; liver; pharynx; blood; umbilical cord; vascular; muscle; tonsil; connective tissue; stomach; spleen; heart; adrenal gland; nerve; pituitary gland; lymph node; cervix; epididymis; bone; bone marrow; larynx; ascites; pineal gland; parathyroid; bladder; adipose tissue; amniotic fluid; ganglia; ear; spinal cord; peritoneum
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q12-q13
UniSTS entry: Chr 11 T03687
UniSTS entry: Chr 11 D11S4371
UniSTS entry: Chr 11 RH11844 [Map Viewer]
UniSTS entry: Chr 11 G19976
UniSTS entry: Chr 11 A002C24 [Map Viewer]
UniSTS entry: Chr 11 RH78281 [Map Viewer]
UniSTS entry: Chr 11 MARC_21157-21158:1025280537:1
UniSTS entry: Chr 11 MARC_15735-15736:1032190398:5
UniSTS entry: Chr 11 DDB1
UniSTS entry: Chr 11 D11S952E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BC051764.2 Homo sapiens damage-specific DNA binding protein 1, 127kDa, mRNA (cDNA clone MGC:54119 IMAGE:6063274), complete cds PA
BC050530.1 Homo sapiens damage-specific DNA binding protein 1, 127kDa, mRNA (cDNA clone MGC:57561 IMAGE:5563018), complete cds PA
NM_001923.4 Homo sapiens damage-specific DNA binding protein 1, 127kDa (DDB1), mRNA PA
U18299.1 Human damage-specific DNA binding protein DDBa p127 subunit (DDB1) mRNA, complete cds P
U32986.1 Human xeroderma pigmentosum group E UV-damaged DNA binding factor mRNA, complete cds PA
L40326.1 Homo sapiens Hepatitis B virus X-associated protein 1 mRNA, complete cds P
BC011686.2 Homo sapiens damage-specific DNA binding protein 1, 127kDa, mRNA (cDNA clone MGC:19563 IMAGE:3845478), complete cds PA
AK311476.1 Homo sapiens cDNA, FLJ18518 P
AK311112.1 Homo sapiens cDNA, FLJ18154
AK312436.1 Homo sapiens cDNA, FLJ92782, highly similar to Homo sapiens damage-specific DNA binding protein 1, 127kDa (DDB1), mRNA P
AK294341.1 Homo sapiens cDNA FLJ52436 complete cds, highly similar to DNA damage-binding protein 1 P
AK303032.1 Homo sapiens cDNA FLJ51165 complete cds, highly similar to DNA damage-binding protein 1 P
BC032080.1 Homo sapiens damage-specific DNA binding protein 1, 127kDa, mRNA (cDNA clone IMAGE:5122376) PA
BC021044.1 Homo sapiens damage-specific DNA binding protein 1, 127kDa, mRNA (cDNA clone IMAGE:2907109) PA
AK302924.1 Homo sapiens cDNA FLJ51163 complete cds, highly similar to DNA damage-binding protein 1 P
AK294493.1 Homo sapiens cDNA FLJ56068 complete cds, highly similar to DNA damage-binding protein 1 P
AJ002955.1 Homo sapiens mRNA for xeroderma pigmentosum complementation group E protein P

EST sequences (10 of 1837) [Show all sequences]

AA863437.1 Clone IMAGE:1456919 kidney 3' read PA
AA972755.1 Clone IMAGE:1585098 lung 3' read A
AA976520.1 Clone IMAGE:1587840 uncharacterized tissue 3' read A
T05546.1 Clone HFBDC16 brain
AI026969.1 Clone IMAGE:1649366 parathyroid 3' read A
AI031775.1 Clone IMAGE:1649935 parathyroid 3' read A
AI033754.1 Clone IMAGE:1647637 parathyroid 3' read
AI056391.1 Clone IMAGE:1669085 brain 3' read A
AI057214.1 Clone IMAGE:1674995 mixed 3' read
AI092901.1 Clone IMAGE:1688815 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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