> MUS81 endonuclease homolog (S. cerevisiae) (MUS81)
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UGID:178413     UniGene Hs.288798     Homo sapiens (human)   MUS81 Order cDNA clone, Links
MUS81 endonuclease homolog (S. cerevisiae) (MUS81)

Human protein-coding gene MUS81. Represented by 370 ESTs from 190 cDNA libraries. Corresponds to reference sequence NM_025128.4. [UniGene 178413 - Hs.288798]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_079404.3 MUS81 gene product H. sapiens 100.0 550
NP_082153.3 Mus81 gene product M. musculus 88.0 550
NP_998683.1 mus81 gene product D. rerio 58.6 598
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_522066.4 PREDICTED: LOW QUALITY PROTEIN: crossover junction endonuclease MUS81 P. troglodytes 98.9 550
XP_001112824.1 PREDICTED: crossover junction endonuclease MUS81-like isoform 4 M. mulatta 98.7 550

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; kidney; testis; lymph node; connective tissue; skin; bladder; liver; pancreas; adrenal gland; pituitary gland; mouth; mixed; uterus; lung; vascular; embryonic tissue; intestine; thymus; cervix; lymph; mammary gland; esophagus; placenta; heart; bone; bone marrow; trachea; salivary gland; spleen; ear; blood; stomach; ascites; ovary; prostate; eye; nerve; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13
UniSTS entry: Chr 11 RH36142 [Map Viewer]
UniSTS entry: Chr 11 D11S2297E [Map Viewer]
UniSTS entry: Chr 11 WI-18484 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AK126820.1 Homo sapiens cDNA FLJ44872 fis, clone BRAMY2022320, highly similar to Crossover junction endonuclease MUS81 (EC 3.1.22.-) P
AK223564.1 Homo sapiens mRNA for MUS81 endonuclease homolog, clone: FCC128B08 P
AK024665.1 Homo sapiens cDNA: FLJ21012 fis, clone CAE05180 PA
NM_025128.4 Homo sapiens MUS81 endonuclease homolog (S. cerevisiae) (MUS81), mRNA PA
BC009999.2 Homo sapiens MUS81 endonuclease homolog (S. cerevisiae), mRNA (cDNA clone MGC:14953 IMAGE:4135990), complete cds PA
AF425646.1 Homo sapiens MUS81 endonuclease (MUS81) mRNA, complete cds P

EST sequences (10 of 370) [Show all sequences]

AA989261.1 Clone IMAGE:1604013 lung 3' read A
AI004770.1 Clone IMAGE:1626088 mixed 3' read P
AI027750.1 Clone IMAGE:1644930 testis 3' read
AI078127.1 Clone IMAGE:1676269 embryonic tissue 3' read A
AI161039.1 Clone IMAGE:1715654 placenta 3' read P
BX117949.1 Clone IMAGp998D16616_;_IMAGE:278751 brain P
AI223161.1 Clone IMAGE:1838902 testis 3' read
AI198223.1 Clone IMAGE:1860385 brain 3' read P
AI289132.1 Clone IMAGE:1899247 kidney 3' read A
AI291347.1 Clone IMAGE:1894882 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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