> DEAD (Asp-Glu-Ala-Asp) box helicase 5 (DDX5)
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UGID:175448     UniGene Hs.279806     Homo sapiens (human)   DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5 (DDX5)

Human protein-coding gene DDX5. Represented by 5744 ESTs from 681 cDNA libraries. Corresponds to reference sequence NM_004396.3. [UniGene 175448 - Hs.279806]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001007614.1 Ddx5 gene product R. norvegicus 100.0 614
XP_001109860.1 PREDICTED: probable ATP-dependent RNA helicase DDX5 M. mulatta 100.0 613
XP_003913345.1 PREDICTED: probable ATP-dependent RNA helicase DDX5 isoform 1 P. anubis 100.0 613
NP_001138306.1 DDX5 gene product P. troglodytes 100.0 613
NP_004387.1 DDX5 gene product H. sapiens 100.0 613
XP_850467.1 PREDICTED: probable ATP-dependent RNA helicase DDX5 isoform 2 C. lupus familiaris 100.0 613
XP_001495197.2 PREDICTED: probable ATP-dependent RNA helicase DDX5 E. caballus 100.0 613
NP_001178324.1 DDX5 gene product B. taurus 100.0 613
XP_004013081.1 PREDICTED: probable ATP-dependent RNA helicase DDX5 O. aries 100.0 613
NP_031866.2 Ddx5 gene product M. musculus 99.8 614
XP_002719530.1 PREDICTED: DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 isoform 3 O. cuniculus 99.8 613
XP_001379329.2 PREDICTED: probable ATP-dependent RNA helicase DDX5 M. domestica 99.7 613
XP_001510775.2 PREDICTED: probable ATP-dependent RNA helicase DDX5 O. anatinus 99.5 613
NP_001084230.1 DEAD (Asp-Glu-Ala-Asp) box helicase 5 X. laevis 91.9 607
NP_997777.1 ddx5 gene product D. rerio 91.3 517
NP_731031.1 Rm62, isoform D D. melanogaster 75.0 516
XP_962960.2 ATP-dependent RNA helicase dbp-2 N. crassa 73.8 526
NP_014287.3 Dbp2p S. cerevisiae 71.6 525
XP_001690022.1 DEAD-box RNA helicase C. reinhardtii 71.3 506
NP_175911.1 DEAD-box ATP-dependent RNA helicase 20 A. thaliana 70.0 497
NP_001041134.1 Protein F58E10.3, isoform a C. elegans 68.4 519
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
XP_003211585.1 PREDICTED: probable ATP-dependent RNA helicase DDX5-like M. gallopavo 96.5 595
NP_990158.1 DDX5 gene product G. gallus 96.5 594

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; testis; trachea; thymus; lung; embryonic tissue; spleen; kidney; liver; placenta; mouth; intestine; uncharacterized tissue; pancreas; blood; connective tissue; skin; prostate; eye; stomach; adrenal gland; vascular; mammary gland; heart; mixed; bone marrow; lymph node; pharynx; bone; esophagus; thyroid; pituitary gland; ascites; ovary; bladder; muscle; cervix; nerve; larynx; lymph; ear; ganglia; umbilical cord; parathyroid; adipose tissue; tonsil; salivary gland; epididymis; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q21
UniSTS entry: Chr 17 RH11006
UniSTS entry: Chr 17 D17S1990
UniSTS entry: Chr 17 PMC102575P1
UniSTS entry: Chr 17 RH103168
UniSTS entry: Chr 17 WI-22548 [Map Viewer]
UniSTS entry: Chr 17 DDX5
UniSTS entry: Chr 17 MARC_2724-2725:991933343:1
UniSTS entry: Ddx5
UniSTS entry: Chr 17 RH104075
UniSTS entry: Chr 17 WI-19207 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BT006943.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kDa) mRNA, complete cds P
NM_004396.3 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box helicase 5 (DDX5), mRNA PA
AL133585.1 Homo sapiens mRNA; cDNA DKFZp434E109 (from clone DKFZp434E109) A
BC016027.1 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, mRNA (cDNA clone MGC:1516 IMAGE:3528578), complete cds PA
AK310318.1 Homo sapiens cDNA, FLJ17360 P
AK297905.1 Homo sapiens cDNA FLJ59357 complete cds, highly similar to Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) PA
AK297753.1 Homo sapiens cDNA FLJ53366 complete cds, highly similar to Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) P
AK297192.1 Homo sapiens cDNA FLJ59339 complete cds, highly similar to Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) PA
AB451382.1 Homo sapiens DDX5 mRNA for ATP-dependent RNA helicase DDX5, partial cds, clone: FLJ08070AAAF P
AB451257.1 Homo sapiens DDX5 mRNA for ATP-dependent RNA helicase DDX5, complete cds, clone: FLJ08070AAAN P
AL359063.1 Homo sapiens EST from clone 1090633, 3' end PA
X15729.1 Human mRNA for nuclear p68 protein PA
X52104.1 Human mRNA for p68 protein PA

EST sequences (10 of 5744) [Show all sequences]

AA962567.1 Clone IMAGE:1553630 kidney 3' read A
AA974702.1 Clone IMAGE:1578263 mixed 3' read P
AA975537.1 Clone IMAGE:1558227 lung 3' read
AA977719.1 Clone IMAGE:1589522 kidney 3' read A
AA985164.1 Clone IMAGE:1629296 brain 3' read P
AA987202.1 Clone IMAGE:1603285 lung 3' read A
AI000218.1 Clone IMAGE:1613838 uncharacterized tissue 3' read P
AI002751.1 Clone IMAGE:1684113 brain 3' read A
AI002799.1 Clone IMAGE:1683777 brain 3' read A
AI002970.1 Clone IMAGE:1699542 kidney 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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