Secreted frizzled-related protein 5 (SFRP5)

Restricted Expression:

normal [show more like this]

juvenile [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

eye; pancreas; brain; intestine; nerve; ganglia

NCBI

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Finding cDNAs

UGID:175342 UniGene Hs.279565 Homo sapiens (human) SFRP5

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Secreted frizzled-related protein 5 (SFRP5)

Human protein-coding gene SFRP5. Represented by 30 ESTs from 11 cDNA libraries. EST representation biased toward normal; juvenile. Corresponds to reference sequence NM_003015.3. [UniGene 175342 - Hs.279565]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_003006.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	SFRP5 gene product	H. sapiens	100.0	316
XP_004020355.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: secreted frizzled-related protein 5, partial	O. aries	100.0	186
NP_061250.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Sfrp5 gene product	M. musculus	96.1	310
NP_001083946.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	secreted frizzled-related protein 5 precursor	X. laevis	71.9	288
NP_571933.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	sfrp5 gene product	D. rerio	69.8	295
Other hits (2 of 25) [Show all]		Species	Id(%)	Len(aa)
XP_002718655.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: secreted frizzled-related protein 5	O. cuniculus	98.7	311
NP_776886.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	SFRP5 gene product	B. taurus	98.1	314

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	10
Map position:	10q24.1
UniSTS entry:	Chr 10	RH71469
UniSTS entry:		Sfrp5
UniSTS entry:	Chr 10	SFRP5_V140

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

BC050435.1	Homo sapiens secreted frizzled-related protein 5, mRNA (cDNA clone MGC:54179 IMAGE:6189478), complete cds	PA
NM_003015.3	Homo sapiens secreted frizzled-related protein 5 (SFRP5), mRNA	PA
AF117758.1	Homo sapiens secreted frizzled-related protein 5 (SFRP5) mRNA, complete cds	P
AF017988.1	Homo sapiens secreted apoptosis related protein 3 (SARP3) mRNA, complete cds	P

EST sequences (10 of 30) [Show all sequences]

CD518814.1	Clone IMAGE:30408866	brain	5' read	P
CD673335.1	Clone fg23g02	eye	5' read	P
CK819907.1	Clone IMAGE:5677357	pancreas	3' read	A
CK819908.1	Clone IMAGE:5677357	pancreas	5' read	A
BP329572.1	Clone RCT03796	intestine	5' read	P
BP329610.1	Clone RCT03896	intestine	5' read	P
BF445674.1	Clone IMAGE:4090341	nerve	3' read	A
AL538532.3	Clone CS0DF024YP06	brain	5' read	P
AL567359.3	Clone CS0DF024YP06	brain	3' read
BM141715.1	Clone IMAGE:5677371	pancreas	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria