> Lactate dehydrogenase A (LDHA)
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UGID:131297     UniGene Hs.2795     Homo sapiens (human)   LDHA Order cDNA clone, Links
Lactate dehydrogenase A (LDHA)

Human protein-coding gene LDHA. Represented by 8026 ESTs from 741 cDNA libraries. EST representation biased toward infant. Corresponds to 6 reference sequences (different isoforms). [UniGene 131297 - Hs.2795]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001158886.1 LDHA gene product H. sapiens 100.0 360
NP_001029268.1 LDHA gene product P. troglodytes 100.0 331
XP_001084747.1 PREDICTED: l-lactate dehydrogenase A chain isoform 6 M. mulatta 99.7 360
NP_001129541.2 Ldha gene product M. musculus 95.8 360
NP_001080702.1 lactate dehydrogenase A X. laevis 93.1 331
NP_571321.1 ldha gene product D. rerio 85.6 332
NP_476581.1 Ecdysone-inducible gene L3, isoform A D. melanogaster 72.9 331
NP_496503.1 Protein LDH-1 C. elegans 68.5 332
NP_193459.1 L-lactate dehydrogenase A. thaliana 62.3 341
XP_001695130.1 cell wall protein pherophorin-C10 C. reinhardtii 45.2 250
Other hits (2 of 45) [Show all]SpeciesId(%)Len(aa)
XP_534084.3 PREDICTED: L-lactate dehydrogenase A chain isoform 1 C. lupus familiaris 97.9 331
NP_001138352.1 LDHA gene product E. caballus 97.6 331

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: infant [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; liver; ascites; uncharacterized tissue; testis; intestine; eye; muscle; heart; connective tissue; skin; placenta; lung; kidney; uterus; stomach; mammary gland; prostate; esophagus; blood; ovary; embryonic tissue; cervix; thymus; mixed; pancreas; adrenal gland; bone; lymph; vascular; pharynx; bone marrow; lymph node; mouth; bladder; spleen; salivary gland; larynx; adipose tissue; thyroid; umbilical cord; ganglia; trachea; nerve; pituitary gland; ear; tonsil; epididymis; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15.4
UniSTS entry: Chr 11 D11S4625
UniSTS entry: Chr 11 LDHA
UniSTS entry: Chr 11 GDB:197849
UniSTS entry: Chr 11 RH93049
UniSTS entry: ldhasts2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

AK130587.1 Homo sapiens cDNA FLJ27077 fis, clone SPL02415, highly similar to L-lactate dehydrogenase M chain (EC 1.1.1.27) P
AK130105.1 Homo sapiens cDNA FLJ26595 fis, clone LNF08485, highly similar to L-lactate dehydrogenase M chain (EC 1.1.1.27) P
AK130035.1 Homo sapiens cDNA FLJ26525 fis, clone KDN08365, highly similar to L-lactate dehydrogenase M chain (EC 1.1.1.27) P
NM_005566.3 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 1, mRNA PA
BC067223.1 Homo sapiens lactate dehydrogenase A, mRNA (cDNA clone MGC:72033 IMAGE:4096518), complete cds PA
CR456775.1 Homo sapiens full open reading frame cDNA clone RZPDo834E124D for gene LDHA, lactate dehydrogenase A; complete cds, incl. stopcodon P
CR541714.1 Homo sapiens full open reading frame cDNA clone RZPDo834A0429D for gene LDHA, lactate dehydrogenase A; complete cds, without stopcodon P
AY423727.1 Homo sapiens proliferation-inducing gene 19 protein mRNA, complete cds P
AK223078.1 Homo sapiens mRNA for lactate dehydrogenase A variant, clone: KAT03231 PA
AK026515.1 Homo sapiens cDNA: FLJ22862 fis, clone KAT01966, highly similar to HSLDHAR Human mRNA for lactate dehydrogenase-A PA
AK307477.1 Homo sapiens cDNA, FLJ97425 P
AK296667.1 Homo sapiens cDNA FLJ54086 complete cds, moderately similar to L-lactate dehydrogenase A chain (EC 1.1.1.27) P
AK296089.1 Homo sapiens cDNA FLJ52549 complete cds, highly similar to L-lactate dehydrogenase A chain (EC 1.1.1.27) P
NM_001135239.1 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 2, mRNA PA
AK298834.1 Homo sapiens cDNA FLJ55792 complete cds, highly similar to L-lactate dehydrogenase A chain (EC 1.1.1.27) P
X02152.1 Human mRNA for lactate dehydrogenase-A (LDH-A, EC 1.1.1.27) P
NM_001165416.1 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 5, mRNA PA
NM_001165415.1 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 4, mRNA PA
NM_001165414.1 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 3, mRNA PA
NR_028500.1 Homo sapiens lactate dehydrogenase A (LDHA), transcript variant 6, non-coding RNA PA

EST sequences (10 of 8026) [Show all sequences]

AA953634.1 Clone IMAGE:1591200 kidney 3' read A
AA962754.1 Clone IMAGE:1573416 kidney 3' read A
AA969812.1 Clone IMAGE:1572720 kidney 3' read A
AA988264.1 Clone IMAGE:1605502 kidney 3' read A
AI000278.1 Clone IMAGE:1636917 kidney 3' read A
AI037996.1 Clone IMAGE:1663894 skin 3' read A
AI075409.1 Clone IMAGE:1679374 skin 3' read A
AI073727.1 Clone IMAGE:1664885 skin 3' read A
AI077656.1 Clone IMAGE:1664447 skin 3' read A
AI082056.1 Clone IMAGE:1678982 skin 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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