Docking protein 6 (DOK6)

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UGID:174817 UniGene Hs.278285 Homo sapiens (human) DOK6

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Docking protein 6 (DOK6)

Human protein-coding gene DOK6. Represented by 81 ESTs from 49 cDNA libraries. Corresponds to reference sequence NM_152721.5. [UniGene 174817 - Hs.278285]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001034262.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Dok6 gene product	M. musculus	100.0	330
XP_574185.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	R. norvegicus	100.0	330
XP_001094756.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	M. mulatta	100.0	330
XP_512169.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6 isoform 2	P. troglodytes	100.0	330
NP_689934.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	DOK6 gene product	H. sapiens	100.0	330
XP_003914519.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	P. anubis	100.0	313
XP_533379.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	C. lupus familiaris	100.0	308
XP_001493142.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	E. caballus	99.7	330
XP_002697712.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	B. taurus	99.7	330
XP_004020649.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	O. aries	99.7	308
NP_001082908.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	dok6 gene product	D. rerio	90.6	329
NP_001080630.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	docking protein 4	X. laevis	64.0	275
Other hits (2 of 15) [Show all]		Species	Id(%)	Len(aa)
XP_002713683.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: docking protein 6	O. cuniculus	99.3	308
XP_002186543.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: similar to docking protein 6, partial	T. guttata	99.2	264

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; placenta; eye; mixed; uncharacterized tissue; connective tissue; ganglia; muscle; testis; pancreas; ovary; ear; parathyroid; kidney

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	18
Map position:	18q22.2
UniSTS entry:	Chr 18	SHGC-35944
UniSTS entry:	Chr 18	RH78400
UniSTS entry:	Chr 18	SGC35852	[Map Viewer]
UniSTS entry:	Chr 18	SHGC-36873	[Map Viewer]
UniSTS entry:	Chr 18	D18S946E
UniSTS entry:		RH78533
UniSTS entry:	Chr 18	RH118621

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AY599248.1	Homo sapiens downstream of tyrosine kinase 6 (DOK6) mRNA, complete cds	PA
BC096744.1	Homo sapiens docking protein 6, mRNA (cDNA clone MGC:104528 IMAGE:5260167), complete cds	PA
AL512695.1	Homo sapiens mRNA; cDNA DKFZp547G133 (from clone DKFZp547G133)	A
BC008583.1	Homo sapiens docking protein 6, mRNA (cDNA clone IMAGE:4214491), partial cds	PA
AK057795.1	Homo sapiens cDNA FLJ25066 fis, clone CBL05086	P
BC019045.2	Homo sapiens docking protein 6, mRNA (cDNA clone IMAGE:4635165), partial cds	PA
NM_152721.5	Homo sapiens docking protein 6 (DOK6), mRNA	PA

EST sequences (10 of 81) [Show all sequences]

R15009.1	Clone IMAGE:35837	brain	5' read
AI022989.1	Clone IMAGE:1650922	parathyroid	3' read
BX113522.1	Clone IMAGp998D22161_;_IMAGE:35837	brain		A
AI217408.1	Clone IMAGE:1845460	mixed	3' read	P
AI435465.1	Clone IMAGE:2126360	mixed	3' read
R45697.1	Clone IMAGE:35837	brain	3' read	A
R60499.1	Clone IMAGE:43047	brain	5' read
BX280184.1	Clone IMAGp998D226649_;_IMAGE:2663781	mixed		P
BX327787.2	Clone CS0DI028YH06	placenta	5' read	P
BX357639.2	Clone CS0DI028YH06	placenta	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria