> MutY homolog (E. coli) (MUTYH)
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UGID:173201     UniGene Hs.271353     Homo sapiens (human)   MUTYH Order cDNA clone, Links
MutY homolog (E. coli) (MUTYH)

Human protein-coding gene MUTYH. Represented by 202 ESTs from 109 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 173201 - Hs.271353]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001121897.1 MUTYH gene product H. sapiens 100.0 548
XP_001155767.3 PREDICTED: A/G-specific adenine DNA glycosylase isoform 8 P. troglodytes 99.6 547
NP_573513.2 Mutyh gene product M. musculus 85.8 514
XP_686698.2 PREDICTED: A/G-specific adenine DNA glycosylase D. rerio 63.4 475
NP_193010.2 A/G-specific adenine glycosylase A. thaliana 52.3 390
XP_001701896.1 DNA repair glycosylase C. reinhardtii 51.6 279
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_001101469.2 PREDICTED: a/G-specific adenine DNA glycosylase isoform 2 M. mulatta 97.3 549
XP_003891834.1 PREDICTED: A/G-specific adenine DNA glycosylase isoform 4 P. anubis 97.1 549

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uncharacterized tissue; stomach; intestine; placenta; heart; kidney; pancreas; cervix; thymus; pituitary gland; embryonic tissue; thyroid; liver; skin; lung; testis; blood; ovary; eye; lymph; uterus; prostate; tonsil; ganglia; connective tissue; bone; adipose tissue; lymph node; bone marrow; nerve; mammary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p34.1
UniSTS entry: Chr 1 RH71246 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

NM_012222.2 Homo sapiens mutY homolog (E. coli) (MUTYH), transcript variant alpha1, mRNA PA
AB032920.1 Homo sapiens mRNA for hMYHalpha1, complete cds PA
AB032921.1 Homo sapiens mRNA for hMYHalpha2, complete cds PA
AB032922.1 Homo sapiens mRNA for hMYHalpha3, complete cds PA
AB032923.1 Homo sapiens mRNA for hMYHalpha4, complete cds PA
AB032924.1 Homo sapiens mRNA for hMYHbeta1, complete cds PA
AB032925.1 Homo sapiens mRNA for hMYHbeta3, complete cds PA
AB032926.1 Homo sapiens mRNA for hMYHbeta5, complete cds PA
AB032927.1 Homo sapiens mRNA for hMYHgamma2, complete cds PA
AB032928.1 Homo sapiens mRNA for hMYHgamma3, complete cds PA
AB032929.1 Homo sapiens mRNA for hMYHgamma4, complete cds PA
BC003178.1 Homo sapiens mutY homolog (E. coli), mRNA (cDNA clone MGC:4416 IMAGE:2958002), complete cds PA
NM_001048174.1 Homo sapiens mutY homolog (E. coli) (MUTYH), transcript variant beta3, mRNA PA
NM_001048173.1 Homo sapiens mutY homolog (E. coli) (MUTYH), transcript variant gamma3, mRNA PA
NM_001048172.1 Homo sapiens mutY homolog (E. coli) (MUTYH), transcript variant gamma2, mRNA PA
NM_001048171.1 Homo sapiens mutY homolog (E. coli) (MUTYH), nuclear gene encoding mitochondrial protein, transcript variant alpha3, mRNA PA
NM_001128425.1 Homo sapiens mutY homolog (E. coli) (MUTYH), transcript variant alpha5, mRNA PA
AK293830.1 Homo sapiens cDNA FLJ53724 complete cds, highly similar to A/G-specific adenine DNA glycosylase (EC 3.2.2.-) P
AB025227.1 Homo sapiens mRNA for MutY homolog (hMYH), partial cds

EST sequences (10 of 202) [Show all sequences]

AA970780.1 Clone IMAGE:1560832 mixed 3' read
AA971691.1 Clone IMAGE:1583659 mixed 3' read P
AA993130.1 Clone IMAGE:1620151 testis 3' read
AI140899.1 Clone IMAGE:1690705 mixed 3' read P
CB054615.1 Clone IMAGE:3291632 brain 5' read P
AI183356.1 Clone IMAGE:1732050 heart 3' read PA
AI184447.1 Clone IMAGE:1731955 heart 3' read A
AI382565.1 Clone IMAGE:2020445 brain 3' read
R49993.1 Clone IMAGE:152795 mammary gland 3' read
AI525115.1 prostate 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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