RAB GTPase activating protein 1 (RABGAP1)

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Finding cDNAs

UGID:173199 UniGene Hs.271341 Homo sapiens (human) RABGAP1

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RAB GTPase activating protein 1 (RABGAP1)

Human protein-coding gene RABGAP1. Represented by 248 ESTs from 171 cDNA libraries. Corresponds to reference sequence NM_012197.3. [UniGene 173199 - Hs.271341]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_520242.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rab GTPase-activating protein 1	P. troglodytes	100.0	1068
NP_036329.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	RABGAP1 gene product	H. sapiens	100.0	1068
XP_003911304.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rab GTPase-activating protein 1	P. anubis	99.8	1068
NP_666233.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	rab GTPase-activating protein 1 isoform a	M. musculus	98.5	1063
XP_003201657.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rab GTPase-activating protein 1-like	D. rerio	90.4	1017
NP_001089922.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	RAB GTPase activating protein 1-like	X. laevis	70.9	1041
NP_001024629.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein TBC-11, isoform c	C. elegans	58.2	546
NP_648213.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	GapcenA, isoform A	D. melanogaster	56.7	360
Other hits (2 of 36) [Show all]		Species	Id(%)	Len(aa)
NP_001178338.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	rab GTPase-activating protein 1	B. taurus	99.3	1068
XP_004005700.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: rab GTPase-activating protein 1	O. aries	99.3	1068

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; testis; lymph node; mammary gland; pharynx; adipose tissue; bone marrow; uterus; eye; skin; embryonic tissue; spinal cord; uncharacterized tissue; pancreas; lung; ear; liver; placenta; prostate; mixed; blood; intestine; heart; kidney; nerve; amniotic fluid; mouth; connective tissue; stomach; larynx; thymus; trachea; pineal gland; ascites; muscle; cervix; bone; adrenal gland; thyroid; ganglia; ovary

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	9
Map position:	9q34.11
UniSTS entry:	Chr 9	RH103351
UniSTS entry:	Chr 9	RH12674	[Map Viewer]
UniSTS entry:	Chr 1	D11S2560

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AJ011679.2	Homo sapiens mRNA for Rab6 GTPase activating protein	PA
AL050195.1	Homo sapiens mRNA; cDNA DKFZp586D2123 (from clone DKFZp586D2123); partial cds	P
BC054492.1	Homo sapiens RAB GTPase activating protein 1, mRNA (cDNA clone MGC:54135 IMAGE:5785896), complete cds	PA
NM_012197.3	Homo sapiens RAB GTPase activating protein 1 (RABGAP1), mRNA	P
AK022408.1	Homo sapiens cDNA FLJ12346 fis, clone MAMMA1002297	P
BC020609.1	Homo sapiens RAB GTPase activating protein 1, mRNA (cDNA clone IMAGE:4768130), partial cds	PA
AF161357.1	Homo sapiens HSPC094 mRNA, partial cds	P
AF088073.1	Homo sapiens full length insert cDNA clone ZD96A04	A
AK294531.1	Homo sapiens cDNA FLJ53389 complete cds, highly similar to Homo sapiens RAB GTPase activating protein 1 (RABGAP1), mRNA	P
AB449897.1	Homo sapiens TBC1D11 mRNA for TBC1 domain family, member 11, complete cds	P

EST sequences (10 of 248) [Show all sequences]

AA976232.1	Clone IMAGE:1567702	lung	3' read
AA948302.1	Clone IMAGE:1588254	uncharacterized tissue	3' read	A
AI131100.1	Clone IMAGE:1709216	heart	3' read	A
AI139678.1	Clone IMAGE:1710138	heart	3' read	A
AI144231.1	Clone IMAGE:1706874	heart	3' read	A
AI150865.1	Clone IMAGE:1705310	heart	3' read
BX106596.1	Clone IMAGp998I183712	mixed	5' read	P
AI222920.1	Clone IMAGE:1883281	lung	3' read	A
AI253679.1	Clone IMAGE:2032101	prostate	3' read
CB146346.1	Clone L16HLK3-26-G02	liver	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria