> Paired box 6 (PAX6)
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UGID:172983     UniGene Hs.270303     Homo sapiens (human)   PAX6 Order cDNA clone, Links
Paired box 6 (PAX6)

Human protein-coding gene PAX6. Represented by 254 ESTs from 86 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 172983 - Hs.270303]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001231127.1 Pax6 gene product M. musculus 100.0 435
NP_990397.1 PAX6 gene product G. gallus 100.0 435
XP_003910125.1 PREDICTED: paired box protein Pax-6 isoform 4 P. anubis 100.0 435
NP_001245391.1 PAX6 gene product H. sapiens 100.0 435
NP_001091013.1 PAX6 gene product C. lupus familiaris 100.0 435
XP_004016422.1 PREDICTED: paired box protein Pax-6 isoform 5 O. aries 100.0 435
NP_001075686.1 PAX6 gene product O. cuniculus 100.0 435
NP_037133.1 Pax6 gene product R. norvegicus 100.0 421
NP_001231101.1 paired box protein Pax-6 isoform 1 S. scrofa 100.0 421
NP_001035735.1 PAX6 gene product B. taurus 100.0 421
XP_003954413.1 PREDICTED: LOW QUALITY PROTEIN: paired box protein Pax-6 P. troglodytes 100.0 391
XP_001084865.2 PREDICTED: paired box protein Pax-6 isoform 1 M. mulatta 99.8 456
XP_003214737.1 PREDICTED: paired box protein Pax-6-like isoform 3 A. carolinensis 99.8 435
XP_001368528.2 PREDICTED: paired box protein Pax-6 isoform 1 M. domestica 99.7 552
NP_001079413.1 paired box 6 X. laevis 98.4 426
NP_571379.1 pax6a gene product D. rerio 97.0 431
NP_524638.3 twin of eyeless, isoform A D. melanogaster 69.4 516
NP_001024570.1 Protein VAB-3, isoform a C. elegans 64.8 421
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_001918200.2 PREDICTED: paired box protein Pax-6 E. caballus 99.2 394
XP_003206127.1 PREDICTED: paired box protein Pax-6-like M. gallopavo 99.2 243

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; eye; intestine; stomach; mixed; pineal gland; kidney; testis; uncharacterized tissue; lung; uterus; pituitary gland; skin; embryonic tissue; mouth; bone; muscle; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p13
UniSTS entry: Chr 11 GDB:197570
UniSTS entry: RH79881
UniSTS entry: Chr 11 GDB:316221
UniSTS entry: Chr 11 GDB:344354
UniSTS entry: RH78222
UniSTS entry: Chr 11 D12Bir2
UniSTS entry: Chr 11 Pax6
UniSTS entry: Pax6
UniSTS entry: Chr 11 RH46063
UniSTS entry: Chr 11 GDB:344736
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

M93650.1 Human paired box gene (PAX6) homologue, complete cds PA
BX640762.1 Homo sapiens mRNA; cDNA DKFZp686B14266 (from clone DKFZp686B14266) PA
NM_000280.4 Homo sapiens paired box 6 (PAX6), transcript variant 1, mRNA PA
NM_001604.5 Homo sapiens paired box 6 (PAX6), transcript variant 2, mRNA PA
AY707088.1 Homo sapiens paired box gene 6 isoform a mRNA, complete cds P
BC011953.1 Homo sapiens paired box 6, mRNA (cDNA clone MGC:17209 IMAGE:3880468), complete cds PA
AY047583.1 Homo sapiens paired box protein PAX6 (PAX6) mRNA, complete cds P
AK314470.1 Homo sapiens cDNA, FLJ95274 P
NM_001127612.1 Homo sapiens paired box 6 (PAX6), transcript variant 3, mRNA PA
AK094249.1 Homo sapiens cDNA FLJ36930 fis, clone BRACE2005251, highly similar to PAIRED BOX PROTEIN PAX-6 P
AK074881.1 Homo sapiens cDNA FLJ90400 fis, clone NT2RP2005941, highly similar to Paired box protein Pax-6 P
M77844.1 Homo sapiens oculorhombin (PAX6) mRNA, complete cds, alternatively spliced PA
GQ141695.1 Homo sapiens paired box protein 6 isoform c (PAX6) mRNA, complete cds, alternatively spliced PA
AB593094.1 Homo sapiens PAX6 mRNA for paired box protein Pax-6, complete cds, clone: HP06376-ARi61A11 PA
AB593093.1 Homo sapiens PAX6 mRNA for paired box protein Pax-6, complete cds, clone: HP06376-ARh11B12 PA
AB593092.1 Homo sapiens PAX6 mRNA for paired box protein Pax-6, complete cds, clone: HP06376-ARe92D06 PA
NM_001258465.1 Homo sapiens paired box 6 (PAX6), transcript variant 7, mRNA PA
NM_001258463.1 Homo sapiens paired box 6 (PAX6), transcript variant 5, mRNA PA
NM_001258464.1 Homo sapiens paired box 6 (PAX6), transcript variant 6, mRNA PA
NM_001258462.1 Homo sapiens paired box 6 (PAX6), transcript variant 4, mRNA PA

EST sequences (10 of 254) [Show all sequences]

R17650.1 Clone IMAGE:32366 brain 5' read
BX114225.1 Clone IMAGp998N244247_;_IMAGE:1673303 mixed
BX089704.1 Clone IMAGp998L13153_;_IMAGE:32366 brain A
AI337595.1 Clone IMAGE:1998409 brain 3' read P
AI522146.1 Clone IMAGE:2138160 kidney 3' read
R43366.1 Clone IMAGE:32366 brain 3' read A
AI652359.1 Clone IMAGE:2310081 uncharacterized tissue 3' read P
T09185.1 Clone HIBBQ26 brain 5' read P
BX281768.1 Clone IMAGp998O1410106_;_IMAGE:4400869 intestine P
AI921916.1 Clone IMAGE:2452729 uterus 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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