> Glycine receptor, alpha 2 (GLRA2)
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UGID:131279     UniGene Hs.2700     Homo sapiens (human)   GLRA2 Order cDNA clone, Links
Glycine receptor, alpha 2 (GLRA2)

Human protein-coding gene GLRA2. Represented by 112 ESTs from 32 cDNA libraries. EST representation biased toward fetus. Corresponds to 4 reference sequences (different isoforms). [UniGene 131279 - Hs.2700]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_002806195.1 PREDICTED: glycine receptor subunit alpha-2 M. mulatta 100.0 451
XP_003917473.1 PREDICTED: glycine receptor subunit alpha-2 isoform 1 P. anubis 100.0 451
XP_001137132.1 PREDICTED: glycine receptor subunit alpha-2 isoform 8 P. troglodytes 100.0 451
NP_001112357.1 GLRA2 gene product H. sapiens 100.0 451
XP_003435502.1 PREDICTED: glycine receptor subunit alpha-2 C. lupus familiaris 100.0 451
XP_001489514.2 PREDICTED: glycine receptor subunit alpha-2 isoform 1 E. caballus 100.0 451
XP_002719958.1 PREDICTED: glycine receptor, alpha 2-like isoform 1 O. cuniculus 100.0 451
XP_001926528.3 PREDICTED: glycine receptor subunit alpha-2 S. scrofa 100.0 362
NP_906272.1 Glra2 gene product M. musculus 99.8 451
XP_003752086.1 PREDICTED: glycine receptor subunit alpha-2-like isoform 1 R. norvegicus 99.8 451
XP_004021964.1 PREDICTED: glycine receptor subunit alpha-2 isoform 1 O. aries 99.6 451
NP_001161371.1 glra2 gene product D. rerio 89.5 447
NP_001163655.1 GluClalpha, isoform F D. melanogaster 52.6 306
NP_504441.1 Protein GLC-3 C. elegans 49.5 307
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
NP_001179843.1 GLRA2 gene product B. taurus 99.3 451
XP_001516922.1 PREDICTED: glycine receptor subunit alpha-2 isoform 1 O. anatinus 98.7 451

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; kidney; ovary; mixed; eye; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp22.2
UniSTS entry: Chr X GDB:604017
UniSTS entry: Chr X RH71280 [Map Viewer]
UniSTS entry: Chr X GLYRA1
UniSTS entry: Chr X GLRA2
UniSTS entry: Chr X GLRA2_2389
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

BC045547.1 Homo sapiens cDNA clone IMAGE:5302075, containing frame-shift errors PA
NM_002063.3 Homo sapiens glycine receptor, alpha 2 (GLRA2), transcript variant 1, mRNA PA
AY437084.1 Homo sapiens glycine receptor alpha2 subunit B (GLRA2) mRNA, complete cds, alternatively spliced P
AY437083.1 Homo sapiens glycine receptor alpha2 subunit A (GLRA2) mRNA, complete cds, alternatively spliced P
CR450343.1 Homo sapiens full open reading frame cDNA clone RZPDo834E082D for gene GLRA2, glycine receptor, alpha 2; complete cds; without stopcodon P
AK289561.1 Homo sapiens cDNA FLJ77741 complete cds, highly similar to Homo sapiens glycine receptor, alpha 2 (GLRA2), mRNA P
AK312591.1 Homo sapiens cDNA, FLJ92967, Homo sapiens glycine receptor, alpha 2 (GLRA2), mRNA P
NM_001118886.1 Homo sapiens glycine receptor, alpha 2 (GLRA2), transcript variant 3, mRNA PA
NM_001118885.1 Homo sapiens glycine receptor, alpha 2 (GLRA2), transcript variant 2, mRNA PA
X52008.1 H.sapiens alpha-2 strychnine binding subunit of inhibitory glycine receptor mRNA P
AK297304.1 Homo sapiens cDNA FLJ57325 complete cds, highly similar to Glycine receptor alpha-2 chain precursor P
AK297268.1 Homo sapiens cDNA FLJ52443 complete cds, highly similar to Glycine receptor alpha-2 chain precursor P
NM_001171942.1 Homo sapiens glycine receptor, alpha 2 (GLRA2), transcript variant 4, mRNA PA
BC032864.2 Homo sapiens glycine receptor, alpha 2, mRNA (cDNA clone MGC:33824 IMAGE:5263356), complete cds PA

EST sequences (10 of 112) [Show all sequences]

AW887021.1 ovary
BP201412.1 Clone AMR05440 brain 5' read P
DN992290.1 Clone TC110908 brain 5' read
DR001325.1 Clone TC122177 brain 5' read P
AV729257.2 Clone HTCCHE03 brain 5' read P
DA117486.1 Clone BRACE3037181 brain 5' read P
DA163725.1 Clone BRAMY2024391 brain 5' read
DA166801.1 Clone BRAMY2028124 brain 5' read
DA247911.1 Clone BRAWH3047210 brain 5' read
DA074294.1 Clone BRACE2025720 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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