> Phospholipase C, gamma 1 (PLCG1)
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UGID:172401     UniGene Hs.268177     Homo sapiens (human)   PLCG1 Order cDNA clone, Links
Phospholipase C, gamma 1 (PLCG1)

Human protein-coding gene PLCG1. Represented by 352 ESTs from 194 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 172401 - Hs.268177]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_514650.3 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 P. troglodytes 100.0 1290
NP_002651.2 PLCG1 gene product H. sapiens 100.0 1290
XP_001087295.2 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 M. mulatta 99.8 1325
NP_067255.2 Plcg1 gene product M. musculus 98.5 1282
NP_001082278.1 phospholipase C, gamma 1 X. laevis 88.7 1269
NP_919388.1 plcg1 gene product D. rerio 83.8 1311
XP_964868.2 elongation factor 1-alpha N. crassa 63.1 176
NP_009676.1 Tef2p S. cerevisiae 61.4 176
NP_200847.1 Elongation factor 1-alpha A. thaliana 56.2 176
NP_872244.1 Protein EEF-1A.2, isoform d C. elegans 54.4 204
NP_476726.2 small wing D. melanogaster 53.7 1090
Other hits (2 of 64) [Show all]SpeciesId(%)Len(aa)
XP_001500255.3 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1-like E. caballus 99.0 1217
XP_003904789.1 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 P. anubis 98.8 1347

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; uncharacterized tissue; intestine; kidney; placenta; liver; lung; thyroid; testis; eye; thymus; mixed; uterus; heart; mammary gland; vascular; trachea; skin; esophagus; prostate; adipose tissue; muscle; pancreas; pharynx; bone marrow; lymph node; ovary; stomach; blood; connective tissue; mouth; amniotic fluid; nerve; ganglia; bone; lymph
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q12-q13.1
UniSTS entry: Chr 20 STS-R76690
UniSTS entry: Chr 20 MARC_13623-13624:1002811759:1
UniSTS entry: Chr 20 STS-M34667 [Map Viewer]
UniSTS entry: Chr 20 G15919
UniSTS entry: Chr 1 SHGC-178
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

M34667.1 Human phospholipase C-gamma mRNA, complete cds P
AL110247.1 Homo sapiens mRNA; cDNA DKFZp434N101 (from clone DKFZp434N101) PA
NM_182811.1 Homo sapiens phospholipase C, gamma 1 (PLCG1), transcript variant 2, mRNA P
NM_002660.2 Homo sapiens phospholipase C, gamma 1 (PLCG1), transcript variant 1, mRNA P
AB210028.1 Homo sapiens mRNA for PLCG1 variant protein, partial cds, clone: hh03521 P
BC131750.1 Homo sapiens cDNA clone IMAGE:40118512
AK309606.1 Homo sapiens cDNA, FLJ99647 P
AK098745.1 Homo sapiens cDNA FLJ25879 fis, clone CBR02568
AK297370.1 Homo sapiens cDNA FLJ60301 complete cds, highly similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) P
AF147391.1 Homo sapiens full length insert cDNA clone YI61E07 A
BC144136.1 Homo sapiens phospholipase C, gamma 1, mRNA (cDNA clone MGC:177673 IMAGE:9052656), complete cds P
BC136466.1 Homo sapiens phospholipase C, gamma 1, mRNA (cDNA clone MGC:168078 IMAGE:9020455), complete cds P
HQ013235.1 Homo sapiens clone pSWD3-5 minisatellite-associated sequence

EST sequences (10 of 352) [Show all sequences]

AA902444.1 Clone IMAGE:1521285 lung 3' read A
AA927359.1 Clone IMAGE:1552476 uncharacterized tissue 3' read A
R24321.1 Clone IMAGE:33883 brain 5' read
AI187110.1 Clone IMAGE:1741267 lung 3' read A
AI223098.1 Clone IMAGE:1837837 testis 3' read
AI264331.1 Clone IMAGE:1855982 mixed 3' read
CB112613.1 Clone L5HLK1-14-E01 liver 5' read
AA285313.1 thymus
AA906587.1 Clone IMAGE:1524205 mixed 3' read
T07067.1 Clone HFBED20 brain P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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