> CCR4-NOT transcription complex, subunit 8 (CNOT8)
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UGID:135271     UniGene Hs.26703     Homo sapiens (human)   CNOT8 Order cDNA clone, Links
CCR4-NOT transcription complex, subunit 8 (CNOT8)

Human protein-coding gene CNOT8. Represented by 578 ESTs from 244 cDNA libraries. Corresponds to reference sequence NM_004779.4. [UniGene 135271 - Hs.26703]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_081225.1 Cnot8 gene product M. musculus 100.0 291
NP_001008383.1 Cnot8 gene product R. norvegicus 100.0 291
XP_001369646.1 PREDICTED: CCR4-NOT transcription complex subunit 8-like M. domestica 100.0 291
XP_001112661.1 PREDICTED: CCR4-NOT transcription complex subunit 8 isoform 5 M. mulatta 100.0 291
XP_003900463.1 PREDICTED: CCR4-NOT transcription complex subunit 8 isoform 1 P. anubis 100.0 291
NP_001233465.1 CNOT8 gene product P. troglodytes 100.0 291
NP_004770.4 CNOT8 gene product H. sapiens 100.0 291
XP_546280.1 PREDICTED: CCR4-NOT transcription complex subunit 8 C. lupus familiaris 100.0 291
XP_001917476.2 PREDICTED: LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 8-like E. caballus 100.0 291
XP_003134168.1 PREDICTED: CCR4-NOT transcription complex subunit 8-like isoform 1 S. scrofa 100.0 291
NP_001179703.1 CCR4-NOT transcription complex subunit 8 B. taurus 100.0 291
XP_004009055.1 PREDICTED: CCR4-NOT transcription complex subunit 8 isoform 1 O. aries 100.0 291
XP_002710380.1 PREDICTED: CCR4-NOT transcription complex, subunit 8-like O. cuniculus 100.0 291
NP_001080119.1 CCR4-NOT transcription complex, subunit 8 X. laevis 98.3 288
NP_998644.1 cnot8 gene product D. rerio 91.4 280
NP_729775.1 Pop2, isoform B D. melanogaster 74.0 289
XP_001697447.1 CCR4-associated factor C. reinhardtii 60.1 270
NP_178193.1 putative CCR4-associated factor 1-6 A. thaliana 56.3 270
XP_959029.1 CCR4-NOT transcription complex subunit 7 N. crassa 49.8 295
NP_499553.1 Protein CCF-1 C. elegans 49.6 262
NP_014450.3 Pop2p S. cerevisiae 45.9 159
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_003428637.1 PREDICTED: LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 8-like O. anatinus 99.3 300
NP_001025789.1 CNOT8 gene product G. gallus 99.3 291

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; uterus; lung; blood; skin; mouth; connective tissue; adrenal gland; lymph; muscle; thyroid; vascular; spleen; eye; pancreas; embryonic tissue; thymus; kidney; lymph node; mixed; intestine; placenta; salivary gland; stomach; bladder; prostate; mammary gland; bone marrow; liver; parathyroid; trachea; esophagus; heart; cervix; ascites; nerve; ganglia; bone; ovary; larynx; ear; tonsil; adipose tissue; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q31-q33
UniSTS entry: Chr 5 A004P22
UniSTS entry: Chr 5 SGC32815 [Map Viewer]
UniSTS entry: Chr 5 RH65257 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

BT006857.1 Homo sapiens CCR4-NOT transcription complex, subunit 8 mRNA, complete cds P
AF053318.1 Homo sapiens CCR4-associated factor 1 (POP2) mRNA, complete cds PA
AF087844.1 Homo sapiens CAF2 mRNA, complete cds PA
BX647124.1 Homo sapiens mRNA; cDNA DKFZp686M1099 (from clone DKFZp686M1099) PA
NM_004779.4 Homo sapiens CCR4-NOT transcription complex, subunit 8 (CNOT8), mRNA PA
AL122045.1 Homo sapiens mRNA; cDNA DKFZp434M1515 (from clone DKFZp434M1515) PA
AF180476.1 Homo sapiens CALIFp (CALIF) mRNA, complete cds P
BC093025.1 Homo sapiens cDNA clone IMAGE:30344920, containing frame-shift errors PA
AK025358.1 Homo sapiens cDNA: FLJ21705 fis, clone COL09940 PA
BC017366.2 Homo sapiens CCR4-NOT transcription complex, subunit 8, mRNA (cDNA clone MGC:1191 IMAGE:3506054), complete cds PA
AK314317.1 Homo sapiens cDNA, FLJ95075, highly similar to Homo sapiens CCR4-NOT transcription complex, subunit 8 (CNOT8), mRNA P
AK315864.1 Homo sapiens cDNA, FLJ79513 complete cds, highly similar to CCR4-NOT transcription complex subunit 8 P
AK309359.1 Homo sapiens cDNA, FLJ99400 P
AK316269.1 Homo sapiens cDNA, FLJ79168 complete cds, highly similar to CCR4-NOT transcription complex subunit 8 P
AK316221.1 Homo sapiens cDNA, FLJ79120 complete cds, highly similar to CCR4-NOT transcription complex subunit 8 P
AK316055.1 Homo sapiens cDNA, FLJ78954 complete cds, highly similar to CCR4-NOT transcription complex subunit 8 P
AK303775.1 Homo sapiens cDNA FLJ52044 complete cds, moderately similar to CCR4-NOT transcription complex subunit 8 P
AK299589.1 Homo sapiens cDNA FLJ52273 complete cds, highly similar to CCR4-NOT transcription complex subunit 8 P
AK297381.1 Homo sapiens cDNA FLJ50580 complete cds, highly similar to CCR4-NOT transcription complex subunit 8 P

EST sequences (10 of 578) [Show all sequences]

AA962304.1 Clone IMAGE:1569910 lung 3' read
AA971905.1 Clone IMAGE:1583199 mixed 3' read
AA994040.1 Clone IMAGE:1628428 mixed 3' read
AA994041.1 Clone IMAGE:1628432 mixed 3' read
AI040041.1 Clone IMAGE:1664327 skin 3' read A
AI051439.1 Clone IMAGE:1648200 parathyroid 3' read A
AI066751.1 Clone IMAGE:1638379 testis 3' read
AI081067.1 Clone IMAGE:1638289 testis 3' read A
AI088469.1 Clone IMAGE:1695614 uterus 3' read A
AI084370.1 Clone IMAGE:1668280 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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