> Mannosidase, alpha, class 2C, member 1 (MAN2C1)
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UGID:135178     UniGene Hs.26232     Homo sapiens (human)   MAN2C1
Mannosidase, alpha, class 2C, member 1 (MAN2C1)

Human protein-coding gene MAN2C1. Represented by 611 ESTs from 234 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 135178 - Hs.26232]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001243423.1 MAN2C1 gene product H. sapiens 100.0 1056
XP_003314839.1 PREDICTED: LOW QUALITY PROTEIN: alpha-mannosidase 2C1 P. troglodytes 100.0 966
NP_082912.1 Man2c1 gene product M. musculus 93.7 1038
NP_001084900.1 mannosidase, alpha, class 2C, member 1 X. laevis 74.7 1041
XP_698084.3 PREDICTED: alpha-mannosidase 2C1-like D. rerio 71.9 973
XP_001690386.1 hypothetical protein CHLREDRAFT_144252 C. reinhardtii 55.0 1042
NP_011359.1 Ams1p S. cerevisiae 52.9 678
XP_958488.1 hypothetical protein NCU07404 N. crassa 51.8 762
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
XP_003918982.1 PREDICTED: alpha-mannosidase 2C1 isoform 2 P. anubis 98.8 1056
XP_001102709.2 PREDICTED: alpha-mannosidase 2C1 isoform 2 M. mulatta 98.5 1036

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; thymus; lung; bladder; blood; placenta; embryonic tissue; thyroid; heart; uterus; mixed; trachea; spleen; ovary; adrenal gland; connective tissue; liver; mouth; eye; pancreas; mammary gland; kidney; prostate; intestine; epididymis; bone; lymph; skin; muscle; larynx; umbilical cord; ascites; amniotic fluid; lymph node; stomach; esophagus; salivary gland; nerve; ganglia; cervix; adipose tissue; vascular
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q11-q13
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 15 rs1128933
UniSTS entry: Chr 15 WI-12510 [Map Viewer]
UniSTS entry: Chr 1 D1S3693
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BC050550.1 Homo sapiens mannosidase, alpha, class 2C, member 1, mRNA (cDNA clone MGC:57644 IMAGE:5529534), complete cds PA
BX647111.1 Homo sapiens mRNA; cDNA DKFZp686K24244 (from clone DKFZp686K24244) PA
NM_006715.3 Homo sapiens mannosidase, alpha, class 2C, member 1 (MAN2C1), transcript variant 1, mRNA PA
AL136876.1 Homo sapiens mRNA; cDNA DKFZp434D175 (from clone DKFZp434D175) PA
BC080191.1 Homo sapiens mannosidase, alpha, class 2C, member 1, mRNA (cDNA clone MGC:87979 IMAGE:6149811), complete cds PA
U37248.1 Homo sapiens alpha-mannosidase (6A8) mRNA, complete cds PA
AK225145.1 Homo sapiens mRNA for mannosidase, alpha, class 2C, member 1 variant, clone: CBL07522 PA
AK311065.1 Homo sapiens cDNA, FLJ18107 P
AK295265.1 Homo sapiens cDNA FLJ59120 complete cds, moderately similar to Alpha-mannosidase 2C1 (EC 3.2.1.24) P
AK294892.1 Homo sapiens cDNA FLJ57925 complete cds, highly similar to Alpha-mannosidase 2C1 (EC 3.2.1.24) P
NM_001256495.1 Homo sapiens mannosidase, alpha, class 2C, member 1 (MAN2C1), transcript variant 3, mRNA PA
NM_001256496.1 Homo sapiens mannosidase, alpha, class 2C, member 1 (MAN2C1), transcript variant 4, mRNA PA
NM_001256494.1 Homo sapiens mannosidase, alpha, class 2C, member 1 (MAN2C1), transcript variant 2, mRNA PA
BC038594.1 Homo sapiens mannosidase, alpha, class 2C, member 1, mRNA (cDNA clone IMAGE:5527998), containing frame-shift errors PA
AF044414.2 Homo sapiens alpha mannosidase 6A8B (6a8b) mRNA, complete cds PA

EST sequences (10 of 611) [Show all sequences]

AA836785.1 Clone IMAGE:1422614 kidney
AA975825.1 Clone IMAGE:1558261 lung 3' read A
AI080978.1 Clone IMAGE:1652909 mixed 3' read A
BX100021.1 Clone IMAGp998D02243_;_IMAGE:154705 mammary gland P
BX115346.1 Clone IMAGp998H125554_;_IMAGE:2244539 uncharacterized tissue
BX111851.1 Clone IMAGp998H111963_;_IMAGE:796090 embryonic tissue
AI206884.1 Clone IMAGE:1942245 uncharacterized tissue 3' read
AI271536.1 Clone IMAGE:1857984 mixed 3' read PA
CB153543.1 Clone B1T694954-29-G04 brain 5' read
CB150319.1 Clone C1SNU17s1-2-E07 cervix 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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