> Brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE)
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UGID:171526     UniGene Hs.258314     Homo sapiens (human)   BRE
Brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE)

Human protein-coding gene BRE. Represented by 462 ESTs from 192 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 171526 - Hs.258314]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001100101.2 PREDICTED: BRCA1-A complex subunit BRE isoform 3 M. mulatta 100.0 414
NP_004890.2 BRE gene product H. sapiens 100.0 414
XP_001160262.1 PREDICTED: BRCA1-A complex subunit BRE isoform 5 P. troglodytes 100.0 382
XP_850681.1 PREDICTED: BRCA1-A complex subunit BRE isoform 2 C. lupus familiaris 100.0 382
XP_001502067.1 PREDICTED: BRCA1-A complex subunit BRE-like isoform 1 E. caballus 100.0 382
NP_001095744.1 BRE gene product B. taurus 100.0 382
XP_004005830.1 PREDICTED: BRCA1-A complex subunit BRE isoform 1 O. aries 100.0 382
XP_003908491.1 PREDICTED: BRCA1-A complex subunit BRE isoform 1 P. anubis 100.0 375
NP_653124.1 Bre gene product M. musculus 99.7 382
XP_002709991.1 PREDICTED: brain and reproductive organ-expressed (TNFRSF1A modulator) O. cuniculus 99.7 382
NP_001085651.1 BRCA1-A complex subunit BRE X. laevis 94.5 383
NP_001017777.1 bre gene product D. rerio 88.8 382
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
NP_954891.1 Bre gene product R. norvegicus 99.5 382
XP_003481311.1 PREDICTED: BRCA1-A complex subunit BRE-like S. scrofa 98.9 88

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; brain; testis; skin; uterus; pancreas; mammary gland; prostate; blood; adipose tissue; liver; uncharacterized tissue; ovary; mixed; placenta; pituitary gland; thymus; kidney; heart; eye; muscle; pharynx; lung; cervix; lymph node; intestine; embryonic tissue; adrenal gland; bone; lymph; stomach; bladder; bone marrow; ascites; spleen; nerve; ganglia; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p23.2
UniSTS entry: Chr 2 D2S2556 [Map Viewer]
UniSTS entry: Chr 2 BRE_4464
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AK123076.1 Homo sapiens cDNA FLJ41081 fis, clone ADRGL2009755, highly similar to Homo sapiens brain and reproductive organ-expressed protein (BRE) mRNA P
NM_004899.4 Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 1, mRNA PA
AY438031.1 Homo sapiens BRCA1/BRCA2-containing complex subunit 45 (BRE) mRNA, complete cds P
NM_199191.2 Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 3, mRNA PA
NM_199192.2 Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 5, mRNA PA
NM_199194.2 Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 2, mRNA PA
NM_199193.2 Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 4, mRNA PA
AK000097.1 Homo sapiens cDNA FLJ20090 fis, clone COL04151 PA
BC001251.1 Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator), mRNA (cDNA clone MGC:4974 IMAGE:3456561), complete cds PA
L38616.1 Homo sapiens brain and reproductive organ-expressed protein (BRE) gene, complete cds P
AF420605.1 Homo sapiens BRE alpha a' isoform (BRE) mRNA, complete cds; alternatively spliced P
AF420604.1 Homo sapiens truncated BRE alpha a3+ isoform (BRE) mRNA, complete cds; alternatively spliced P
AF420602.1 Homo sapiens BRE alpha b isoform (BRE) mRNA, complete cds; alternatively spliced P
AK291086.1 Homo sapiens cDNA FLJ77520 complete cds, highly similar to Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 2, mRNA P
AK098345.1 Homo sapiens cDNA FLJ25479 fis, clone CBL03933
AF420603.1 Homo sapiens upstream ORF and BRE beta b isoform (BRE) mRNAs, complete cds; alternatively spliced P
NM_001261840.1 Homo sapiens brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 6, mRNA PA
AF015767.1 Homo sapiens brain and reproductive organ-expressed protein (BRE) mRNA, complete cds P

EST sequences (10 of 462) [Show all sequences]

AA866122.1 Clone IMAGE:1470352 uncharacterized tissue 3' read A
AA906458.1 Clone IMAGE:1506009 mixed 3' read PA
T05448.1 Clone HFBCY60 brain
AA969603.1 Clone IMAGE:1579138 mixed 3' read PA
AI028623.1 Clone IMAGE:1644654 testis 3' read PA
AI074134.1 Clone IMAGE:1679147 skin 3' read A
AI074750.1 Clone IMAGE:1663654 skin 3' read
BX118946.1 Clone IMAGp998D19461_;_IMAGE:229602 mixed P
AI188080.1 Clone IMAGE:1734326 testis 3' read PA
AI191089.1 Clone IMAGE:1740037 lung 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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