SH3-domain binding protein 5 (BTK-associated) (SH3BP5)

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UGID:171309 UniGene Hs.257761 Homo sapiens (human) SH3BP5

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SH3-domain binding protein 5 (BTK-associated) (SH3BP5)

Human protein-coding gene SH3BP5. Represented by 444 ESTs from 196 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 171309 - Hs.257761]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_526142.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: SH3 domain-binding protein 5 isoform 3	P. troglodytes	100.0	454
NP_004835.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	SH3BP5 gene product	H. sapiens	100.0	454
XP_003895182.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: SH3 domain-binding protein 5	P. anubis	99.8	454
NP_036024.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Sh3bp5 gene product	M. musculus	96.9	457
NP_998623.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	sh3bp5b gene product	D. rerio	85.0	414
NP_611010.4 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	parcas	D. melanogaster	50.6	253
Other hits (2 of 30) [Show all]		Species	Id(%)	Len(aa)
XP_002803126.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: SH3 domain-binding protein 5-like, partial	M. mulatta	99.1	336
XP_542777.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: SH3 domain-binding protein 5	C. lupus familiaris	98.5	413

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; lung; placenta; skin; uterus; testis; adrenal gland; uncharacterized tissue; pharynx; mixed; pancreas; pituitary gland; bone marrow; cervix; blood; embryonic tissue; mammary gland; parathyroid; muscle; prostate; eye; kidney; stomach; bone; heart; amniotic fluid; ganglia; connective tissue; spleen; lymph node; liver; intestine; esophagus; thymus; trachea; tonsil; salivary gland; lymph; ear; vascular; umbilical cord; adipose tissue; ovary; thyroid

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	3
Map position:	3p24.3
UniSTS entry:	Chr 3	SHGC-76742	[Map Viewer]
UniSTS entry:	Chr 3	RH66166
UniSTS entry:		D3S3926
UniSTS entry:	Chr 1	SHGC-67307
UniSTS entry:	Chr 1	PMC156606P2
UniSTS entry:	Chr 1	PMC156606P3
UniSTS entry:	Chr 1	PMC156606P4

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AB005047.1	Homo sapiens mRNA for SH3 binding protein, complete cds	P
AL117422.1	Homo sapiens mRNA; cDNA DKFZp586J0724 (from clone DKFZp586J0724)	PA
NM_004844.4	Homo sapiens SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1, mRNA	P
NM_001018009.3	Homo sapiens SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 2, mRNA	P
BC006169.1	Homo sapiens SH3-domain binding protein 5 (BTK-associated), mRNA (cDNA clone IMAGE:4025362)	PA
BC010123.2	Homo sapiens SH3-domain binding protein 5 (BTK-associated), mRNA (cDNA clone MGC:19574 IMAGE:3841593), complete cds	PA
AK313167.1	Homo sapiens cDNA, FLJ93663, Homo sapiens SH3-domain binding protein 5 (BTK-associated)(SH3BP5), mRNA	P
AK090524.1	Homo sapiens cDNA FLJ33205 fis, clone ADRGL2007651, highly similar to SH3 domain-binding protein 5	P
BC023195.1	Homo sapiens SH3-domain binding protein 5 (BTK-associated), mRNA (cDNA clone IMAGE:3882437)	PA

EST sequences (10 of 444) [Show all sequences]

AA974265.1	Clone IMAGE:1586295	uncharacterized tissue	3' read	A
AA994787.1	Clone IMAGE:1631641	mammary gland	3' read	A
AI003583.1	Clone IMAGE:1387898	parathyroid	3' read	A
AI004434.1	Clone IMAGE:1619952	testis	3' read
AI027543.1	Clone IMAGE:1650441	parathyroid	3' read	A
AI034076.1	Clone IMAGE:1656095	mixed	3' read
AI034203.1	Clone IMAGE:1646336	parathyroid	3' read
AI038206.1	Clone IMAGE:1660101	embryonic tissue	3' read	A
AI040074.1	Clone IMAGE:1659916	embryonic tissue	3' read
AI075213.1	Clone IMAGE:1667552	parathyroid	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria