> Methyl-CpG binding domain protein 2 (MBD2)
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UGID:135078     UniGene Hs.25674     Homo sapiens (human)   MBD2
Methyl-CpG binding domain protein 2 (MBD2)

Human protein-coding gene MBD2. Represented by 294 ESTs from 154 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 135078 - Hs.25674]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003918.1 MBD2 gene product H. sapiens 100.0 410
XP_001499825.2 PREDICTED: methyl-CpG-binding domain protein 2-like E. caballus 100.0 268
XP_002697814.1 PREDICTED: methyl-CpG-binding domain protein 2 B. taurus 100.0 198
XP_004020598.1 PREDICTED: methyl-CpG-binding domain protein 2 O. aries 100.0 198
XP_001082249.1 PREDICTED: methyl-CpG-binding domain protein 2 M. mulatta 99.8 411
XP_003914441.1 PREDICTED: methyl-CpG-binding domain protein 2 P. anubis 99.8 411
XP_002713528.1 PREDICTED: methyl-CpG binding domain protein 2 O. cuniculus 99.7 298
NP_034903.2 Mbd2 gene product M. musculus 98.8 413
NP_001083787.1 methyl-CpG binding domain protein 2 X. laevis 90.5 263
NP_997933.1 mbd2 gene product D. rerio 83.0 253
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_512139.4 PREDICTED: methyl-CpG-binding domain protein 2 isoform 3 P. troglodytes 99.3 458
NP_001108497.1 Mbd2 gene product R. norvegicus 98.3 411

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; uncharacterized tissue; uterus; placenta; brain; prostate; skin; liver; parathyroid; intestine; mixed; bone marrow; ear; eye; lung; vascular; muscle; ovary; stomach; bladder; embryonic tissue; adrenal gland; pituitary gland; blood; mammary gland; pancreas; lymph node; larynx; heart; mouth; nerve; ganglia; bone; testis; pharynx; ascites; adipose tissue; thyroid; kidney; esophagus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21
UniSTS entry: Chr 18 SHGC-81536
UniSTS entry: Mbd2
UniSTS entry: Chr 18 RH98619
UniSTS entry: Chr 18 RH36568 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF039701.1 Homo sapiens antigen NY-CO-41 (NY-CO-41) mRNA, partial cds P
AF072242.1 Homo sapiens methyl-CpG binding protein MBD2 (MBD2) mRNA, complete cds PA
AF072246.1 Homo sapiens testis specific methyl-CpG binding protein MBD2 (MBD2) mRNA, partial cds P
NM_003927.4 Homo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 1, mRNA PA
NM_015832.4 Homo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 2, mRNA PA
BC032638.1 Homo sapiens methyl-CpG binding domain protein 2, mRNA (cDNA clone MGC:45085 IMAGE:5496721), complete cds PA
AL110266.1 Homo sapiens mRNA; cDNA DKFZp586O0821 (from clone DKFZp586O0821) A
AF072252.1 Homo sapiens methyl-CpG binding protein MBD2 (MBD2) gene, 3' UTR

EST sequences (10 of 294) [Show all sequences]

AI014977.1 Clone IMAGE:1640768 testis 3' read A
AI049757.1 Clone IMAGE:1699828 kidney 3' read A
AI055997.1 Clone IMAGE:1648532 parathyroid 3' read A
AI074121.1 Clone IMAGE:1679142 skin 3' read A
AI138289.1 Clone IMAGE:1735884 testis 3' read A
AI151139.1 Clone IMAGE:1721208 uterus 3' read A
BX091908.1 Clone IMAGp998I151748_;_IMAGE:713558 ovary P
AI189827.1 Clone IMAGE:1724173 placenta 3' read A
AI209107.1 Clone IMAGE:1838565 testis 3' read A
AI261965.1 Clone IMAGE:1871724 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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