> ADAM metallopeptidase domain 22 (ADAM22)
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UGID:171068     UniGene Hs.256398     Homo sapiens (human)   ADAM22 Order cDNA clone, Links
ADAM metallopeptidase domain 22 (ADAM22)

Human protein-coding gene ADAM22. Represented by 141 ESTs from 80 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 171068 - Hs.256398]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_068369.1 ADAM22 gene product H. sapiens 100.0 905
XP_001164271.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 22 isoform 6 P. troglodytes 99.7 905
NP_001091695.1 disintegrin and metalloproteinase domain-containing protein 22 isoform c precursor M. musculus 93.0 867
NP_001080913.1 disintegrin and metalloproteinase domain-containing protein 22 precursor X. laevis 77.8 923
XP_002665027.2 PREDICTED: disintegrin and metalloproteinase domain-containing protein 22 D. rerio 67.0 957
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_002803443.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 22 isoform 2 M. mulatta 98.8 957
XP_003130167.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 22 isoform 1 S. scrofa 98.0 904

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; muscle; uncharacterized tissue; kidney; mixed; embryonic tissue; ear; pituitary gland; connective tissue; testis; adrenal gland; liver; eye; prostate; intestine; lung; skin; heart; nerve; pharynx; bone; uterus; pancreas; mammary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q21
UniSTS entry: Chr 7 RH93001
UniSTS entry: Chr 7 STS-N29801
UniSTS entry: Chr 7 A002T31 [Map Viewer]
UniSTS entry: Chr 7 RH92490
UniSTS entry: Chr 7 ADAM22_1746
UniSTS entry: Chr 7 RH47331 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AB009671.1 Homo sapiens mRNA for MDC2 alpha, MDC2 beta, complete cds P
AK125432.1 Homo sapiens cDNA FLJ43443 fis, clone OCBBF2031167, highly similar to ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) P
NM_004194.3 Homo sapiens ADAM metallopeptidase domain 22 (ADAM22), transcript variant 4, mRNA P
BC062433.1 Homo sapiens ADAM metallopeptidase domain 22, mRNA (cDNA clone IMAGE:6458074), partial cds PA
AL133090.1 Homo sapiens mRNA; cDNA DKFZp434E0528 (from clone DKFZp434E0528) A
NM_016351.4 Homo sapiens ADAM metallopeptidase domain 22 (ADAM22), transcript variant 3, mRNA PA
AF158637.1 Homo sapiens metalloproteinase-disintegrin ADAM22-3 (ADAM22) mRNA, alternatively spliced, partial cds PA
AF073291.2 Homo sapiens MDC2 (MDC2) mRNA, complete cds P
AF155381.1 Homo sapiens metalloprotease-like, disintegrin-like, cysteine-rich protein 2 delta (ADAM22) mRNA, alternative splice product, complete cds P
AF155382.1 Homo sapiens metalloprotease-like, disintegrin-like, cysteine-rich protein 2 epsilon (ADAM22) mRNA, complete cds P
BC092465.1 Homo sapiens ADAM metallopeptidase domain 22, mRNA (cDNA clone IMAGE:4375012), complete cds PA
NM_021721.3 Homo sapiens ADAM metallopeptidase domain 22 (ADAM22), transcript variant 5, mRNA P
NM_021722.4 Homo sapiens ADAM metallopeptidase domain 22 (ADAM22), transcript variant 2, mRNA PA
NM_021723.3 Homo sapiens ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1, mRNA PA
BC125118.1 Homo sapiens ADAM metallopeptidase domain 22, mRNA (cDNA clone MGC:149832 IMAGE:40118904), complete cds P
BC125117.1 Homo sapiens cDNA clone IMAGE:40118903, containing frame-shift errors P
AK291010.1 Homo sapiens cDNA FLJ77109 complete cds, highly similar to Homo sapiens MDC2 mRNA P
BC036029.1 Homo sapiens ADAM metallopeptidase domain 22, mRNA (cDNA clone IMAGE:5278621), complete cds PA

EST sequences (10 of 141) [Show all sequences]

AA902917.1 Clone IMAGE:1516710 uncharacterized tissue 3' read A
R17521.1 Clone IMAGE:30863 brain 5' read
BX097446.1 Clone IMAGp998P20825_;_IMAGE:359299 heart
AA566127.1 Clone 3Y15 uncharacterized tissue
AA566133.1 Clone 3Y52 uncharacterized tissue
AA566100.1 Clone 3Y283 uncharacterized tissue
AI290223.1 Clone IMAGE:1879080 mixed 3' read A
T08089.1 Clone HIBAB89 brain 5' read
AI457646.1 Clone IMAGE:2146226 mixed 3' read A
AI521937.1 Clone IMAGE:2138844 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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