> Tight junction protein 3 (TJP3)
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UGID:135054     UniGene Hs.25527     Homo sapiens (human)   TJP3
Tight junction protein 3 (TJP3)

Human protein-coding gene TJP3. Represented by 187 ESTs from 82 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 135054 - Hs.25527]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001254490.1 TJP3 gene product H. sapiens 100.0 927
XP_001135804.2 PREDICTED: tight junction protein ZO-3 isoform 2 P. troglodytes 99.7 927
NP_038797.2 Tjp3 gene product M. musculus 84.8 903
NP_001079562.1 tight junction protein 3 X. laevis 61.1 1009
NP_001188500.1 tjp2a gene product D. rerio 50.8 498
Other hits (2 of 26) [Show all]SpeciesId(%)Len(aa)
XP_003914712.1 PREDICTED: tight junction protein ZO-3 isoform 2 P. anubis 97.2 928
XP_001117962.1 PREDICTED: tight junction protein ZO-3-like, partial M. mulatta 97.1 374

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; ovary; intestine; eye; mouth; bladder; pancreas; thyroid; trachea; mixed; esophagus; embryonic tissue; prostate; placenta; lung; mammary gland; uterus; stomach; uncharacterized tissue; liver; cervix; brain; ascites; lymph; connective tissue; spleen; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
UniSTS entry: Chr 19 RH103039
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AK128237.1 Homo sapiens cDNA FLJ46371 fis, clone TESTI4051865, highly similar to Tight junction protein ZO-3 P
BC108906.2 Homo sapiens tight junction protein 3 (zona occludens 3), mRNA (cDNA clone MGC:119546 IMAGE:40008232), complete cds P
BC108907.1 Homo sapiens tight junction protein 3 (zona occludens 3), mRNA (cDNA clone IMAGE:40008235), partial cds P
AK027292.1 Homo sapiens cDNA FLJ14386 fis, clone HEMBA1002417, moderately similar to TIGHT JUNCTION PROTEIN ZO-1 P
AK091118.1 Homo sapiens cDNA FLJ33799 fis, clone CTONG2000201, highly similar to Tight junction protein ZO-3 P
AK304462.1 Homo sapiens cDNA FLJ58409 complete cds, highly similar to Tight junction protein ZO-3 PA
NM_001267561.1 Homo sapiens tight junction protein 3 (TJP3), transcript variant 2, mRNA PA
NM_001267560.1 Homo sapiens tight junction protein 3 (TJP3), transcript variant 1, mRNA PA

EST sequences (10 of 187) [Show all sequences]

AA954879.1 Clone IMAGE:1576252 intestine 3' read P
AA865971.1 Clone IMAGE:1470233 uncharacterized tissue 3' read A
AA983431.1 Clone IMAGE:1598817 uncharacterized tissue 3' read PA
AA993485.1 Clone IMAGE:1621573 testis 3' read PA
AI142918.1 Clone IMAGE:1678281 mixed 3' read PA
BX110112.1 Clone IMAGp998F011780_;_IMAGE:725760 ovary P
AI218504.1 Clone IMAGE:1844882 mixed 3' read PA
CB159368.1 Clone L18POOL1n1-30-G06 liver 5' read P
AA897389.1 Clone IMAGE:1466163 mixed 3' read A
AI248930.1 Clone IMAGE:1849794 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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