> Phosphofructokinase, liver (PFKL)
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UGID:170806     UniGene Hs.255093     Homo sapiens (human)   PFKL Order cDNA clone, Links
Phosphofructokinase, liver (PFKL)

Human protein-coding gene PFKL. Represented by 958 ESTs from 311 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 170806 - Hs.255093]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001150758.1 PREDICTED: 6-phosphofructokinase, liver type isoform 12 P. troglodytes 100.0 779
NP_002617.3 PFKL gene product H. sapiens 100.0 779
NP_032852.2 Pfkl gene product M. musculus 97.4 779
XP_698635.3 PREDICTED: 6-phosphofructokinase, liver type-like D. rerio 83.5 779
NP_001091319.1 phosphofructokinase, platelet X. laevis 76.0 770
NP_724890.1 phosphofructokinase, isoform B D. melanogaster 64.1 758
NP_741738.1 Protein PFK-1, isoform a C. elegans 63.4 768
NP_013932.1 6-phosphofructokinase subunit beta S. cerevisiae 53.5 622
XP_965769.2 6-phosphofructokinase N. crassa 53.3 747
Other hits (2 of 44) [Show all]SpeciesId(%)Len(aa)
XP_003895451.1 PREDICTED: 6-phosphofructokinase, liver type P. anubis 99.4 779
NP_001073713.1 PFKL gene product B. taurus 97.7 779

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; skin; lung; uterus; placenta; eye; embryonic tissue; mixed; lymph; thymus; prostate; vascular; kidney; intestine; blood; pancreas; muscle; mammary gland; bone marrow; cervix; ovary; lymph node; esophagus; nerve; pituitary gland; mouth; stomach; spleen; bone; tonsil; bladder; parathyroid; epididymis; ascites; connective tissue; amniotic fluid; heart; liver; thyroid; ganglia; salivary gland; trachea; adrenal gland; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.3
UniSTS entry: Chr 21 RH47822 [Map Viewer]
UniSTS entry: Chr 21 STS-X15573 [Map Viewer]
UniSTS entry: Chr 21 GDB:185161
UniSTS entry: Pfkl
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

NM_002626.4 Homo sapiens phosphofructokinase, liver (PFKL), transcript variant 2, mRNA P
AB209127.1 Homo sapiens mRNA for liver phosphofructokinase isoform a variant protein P
BC004920.2 Homo sapiens phosphofructokinase, liver, mRNA (cDNA clone IMAGE:3545993), partial cds PA
BC006422.1 Homo sapiens phosphofructokinase, liver, mRNA (cDNA clone MGC:12724 IMAGE:4040291), complete cds PA
BC007536.1 Homo sapiens phosphofructokinase, liver, mRNA (cDNA clone MGC:15386 IMAGE:3347301), complete cds PA
BC008964.2 Homo sapiens phosphofructokinase, liver, mRNA (cDNA clone MGC:4256 IMAGE:3029577), complete cds PA
BC009919.2 Homo sapiens phosphofructokinase, liver, mRNA (cDNA clone MGC:2893 IMAGE:3009907), complete cds PA
BC018295.1 Homo sapiens phosphofructokinase, liver, mRNA (cDNA clone IMAGE:3458877), partial cds PA
AK308437.1 Homo sapiens cDNA, FLJ98385 P
AK091488.1 Homo sapiens cDNA FLJ34169 fis, clone FCBBF3015317, highly similar to 6-PHOSPHOFRUCTOKINASE, LIVER TYPE (EC 2.7.1.11) P
AK303605.1 Homo sapiens cDNA FLJ61026 complete cds, highly similar to Homo sapiens phosphofructokinase, liver (PFKL), transcript variant 1, mRNA P
AF147333.1 Homo sapiens full length insert cDNA clone YB24G09 A
AF086180.1 Homo sapiens full length insert cDNA clone ZB96H01 A
X15573.1 Human liver-type 1-phosphofructokinase (PFKL) mRNA, complete cds P
NR_024108.1 Homo sapiens phosphofructokinase, liver (PFKL), transcript variant 1, non-coding RNA P

EST sequences (10 of 958) [Show all sequences]

AA972053.1 Clone IMAGE:1583945 mixed 3' read A
AI016772.1 Clone IMAGE:1638892 testis 3' read A
AA922214.1 Clone IMAGE:1544075 mixed 3' read
AI075731.1 Clone IMAGE:1676325 embryonic tissue 3' read A
AI082354.1 Clone IMAGE:1670938 uncharacterized tissue 3' read
AI127117.1 Clone IMAGE:1708107 heart 3' read P
AI127165.1 Clone IMAGE:1708200 heart 3' read A
BX113357.1 Clone IMAGp998A15174_;_IMAGE:41473 brain A
AI168833.1 Clone IMAGE:1661414 mixed 3' read
AI186227.1 Clone IMAGE:1731354 heart 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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