> Cathepsin Z (CTSZ)
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UGID:169915     UniGene Hs.252549     Homo sapiens (human)   CTSZ
Cathepsin Z (CTSZ)

Human protein-coding gene CTSZ. Represented by 331 ESTs from 153 cDNA libraries. Corresponds to reference sequence NM_001336.3. [UniGene 169915 - Hs.252549]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001140086.1 PREDICTED: cathepsin Z P. troglodytes 100.0 302
NP_001327.2 CTSZ gene product H. sapiens 100.0 302
NP_071720.1 cathepsin Z preproprotein M. musculus 90.8 293
NP_001085114.1 uncharacterized protein LOC432187 precursor X. laevis 79.2 293
NP_001006043.1 ctsz gene product D. rerio 75.2 294
NP_491023.2 Protein CPZ-1 C. elegans 66.7 242
XP_001702343.1 hypothetical protein CHLREDRAFT_108071 C. reinhardtii 61.4 264
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_003904600.1 PREDICTED: cathepsin Z P. anubis 96.7 302
NP_899159.1 Ctsz gene product R. norvegicus 91.2 296

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; stomach; lung; mixed; uncharacterized tissue; mammary gland; ovary; lymph node; embryonic tissue; thyroid; pharynx; heart; uterus; cervix; placenta; skin; brain; pancreas; kidney; mouth; parathyroid; thymus; spleen; testis; bladder; larynx; eye; prostate; pituitary gland; connective tissue; liver; blood; ascites; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q13.32
UniSTS entry: Chr 20 G62034
UniSTS entry: Chr 20 RH48060 [Map Viewer]
UniSTS entry: Chr 1 G34842
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BC042168.1 Homo sapiens cathepsin Z, mRNA (cDNA clone MGC:52255 IMAGE:5018854), complete cds PA
AF073890.1 Homo sapiens cathepsin X precursor, mRNA, complete cds P
AF009923.1 Homo sapiens preprocathepsin P mRNA, partial cds P
NM_001336.3 Homo sapiens cathepsin Z (CTSZ), mRNA PA
BT019915.1 Homo sapiens cathepsin Z mRNA, complete cds P
AF136273.1 Homo sapiens cathepsin Z precursor (CTSZ) mRNA, complete cds P
AK314931.1 Homo sapiens cDNA, FLJ95840, Homo sapiens cathepsin Z (CTSZ), mRNA P
BC025419.2 Homo sapiens cathepsin Z, mRNA (cDNA clone IMAGE:3929674), containing frame-shift errors PA

EST sequences (10 of 331) [Show all sequences]

AA961056.1 Clone IMAGE:1578809 mixed 3' read P
AA987236.1 Clone IMAGE:1604235 lung 3' read P
AA994147.1 Clone IMAGE:1628572 mixed 3' read P
AI073435.1 Clone IMAGE:1566086 mixed 3' read P
R21196.1 Clone IMAGE:130309 placenta 5' read
AI081224.1 Clone IMAGE:1662249 mixed 3' read P
AI081943.1 Clone IMAGE:1681778 skin 3' read P
R22812.1 Clone IMAGE:130309 placenta 3' read
AI128897.1 Clone IMAGE:1663083 skin 3' read P
CB050774.1 Clone IMAGE:3272316 prostate 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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