> Cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1)
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UGID:134973     UniGene Hs.25121     Homo sapiens (human)   CYP46A1 Order cDNA clone, Links
Cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1)

Human protein-coding gene CYP46A1. Represented by 45 ESTs from 25 cDNA libraries. Corresponds to reference sequence NM_006668.1. [UniGene 134973 - Hs.25121]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006659.1 CYP46A1 gene product H. sapiens 100.0 499
XP_510158.3 PREDICTED: cholesterol 24-hydroxylase isoform 2 P. troglodytes 100.0 402
XP_001103455.2 PREDICTED: cholesterol 24-hydroxylase-like isoform 1 M. mulatta 100.0 392
XP_003902307.1 PREDICTED: cholesterol 24-hydroxylase-like isoform 1 P. anubis 99.8 499
NP_034140.1 Cyp46a1 gene product M. musculus 95.4 499
NP_001104219.1 uncharacterized protein LOC100126648 X. laevis 57.9 492
NP_001018358.1 cyp46a1 gene product D. rerio 52.8 489
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
NP_001102193.1 cholesterol 24-hydroxylase R. norvegicus 95.3 402
XP_537552.3 PREDICTED: cholesterol 24-hydroxylase C. lupus familiaris 94.3 458

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; eye; pancreas; mixed; nerve; heart; muscle; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q32.1
UniSTS entry: Chr 1 PMC22064P1
UniSTS entry: Cyp46a1
UniSTS entry: Chr 14 RH78065
UniSTS entry: Chr 1 sY3084
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_006668.1 Homo sapiens cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1), mRNA PA
AF094480.1 Homo sapiens cholesterol 24-hydroxylase mRNA, complete cds PA
AB209749.1 Homo sapiens mRNA for cytochrome P450, family 46 variant protein P
BC128037.1 Homo sapiens cDNA clone IMAGE:40022895
BC022539.1 Homo sapiens cytochrome P450, family 46, subfamily A, polypeptide 1, mRNA (cDNA clone MGC:26700 IMAGE:4819975), complete cds PA
AK090886.1 Homo sapiens cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to Homo sapiens cholesterol 24-hydroxylase mRNA P
AK295216.1 Homo sapiens cDNA FLJ55970 complete cds, highly similar to Cytochrome p450 46A1 (EC 1.14.13.98) P

EST sequences (10 of 45) [Show all sequences]

AA961615.1 Clone IMAGE:1578399 mixed 3' read A
BX093621.1 Clone IMAGp998N21166_;_IMAGE:38356 brain A
R36281.1 Clone IMAGE:38356 brain 5' read P
AI554732.1 Clone IMAGE:2168869 brain 3' read A
R49568.1 Clone IMAGE:38356 brain 3' read A
CF456253.1 Clone IMAGE:30515362 nerve 5' read P
AW469811.1 Clone IMAGE:2911504 mixed 3' read A
CD623072.1 uncharacterized tissue
CD623073.1 uncharacterized tissue P
CD623074.1 uncharacterized tissue P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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