> Hairy and enhancer of split 1, (Drosophila) (HES1)
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UGID:169726     UniGene Hs.250666     Homo sapiens (human)   HES1 Order cDNA clone, Links
Hairy and enhancer of split 1, (Drosophila) (HES1)

Human protein-coding gene HES1. Represented by 425 ESTs from 140 cDNA libraries. Corresponds to reference sequence NM_005524.3. [UniGene 169726 - Hs.250666]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003895343.1 PREDICTED: transcription factor HES-1 P. anubis 100.0 279
XP_516956.1 PREDICTED: transcription factor HES-1 isoform 3 P. troglodytes 100.0 279
NP_005515.1 HES1 gene product H. sapiens 100.0 279
NP_001029850.1 HES1 gene product B. taurus 100.0 279
XP_001498894.2 PREDICTED: transcription factor HES-1-like, partial E. caballus 100.0 154
NP_077336.3 Hes1 gene product R. norvegicus 99.6 280
NP_001182160.1 HES1 gene product S. scrofa 99.6 279
XP_002716563.1 PREDICTED: hairy and enhancer of split 1 O. cuniculus 99.6 278
NP_032261.1 Hes1 gene product M. musculus 98.9 281
NP_571154.1 her6 gene product D. rerio 89.1 293
NP_001081396.1 transcription factor HES-1-A X. laevis 88.8 266
NP_476923.1 deadpan D. melanogaster 52.5 202
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_004003082.1 PREDICTED: LOW QUALITY PROTEIN: transcription factor HES-1 O. aries 96.4 223
XP_001363166.1 PREDICTED: transcription factor HES-1-like M. domestica 92.4 275

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; eye; mixed; brain; embryonic tissue; uncharacterized tissue; kidney; lung; placenta; prostate; pancreas; intestine; spinal cord; pituitary gland; stomach; testis; mammary gland; uterus; parathyroid; vascular; spleen; blood; nerve; amniotic fluid; ear; mouth; bladder; skin; connective tissue; pharynx; esophagus; ascites; lymph node; thyroid; muscle; heart; umbilical cord; bone; thymus; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q28-q29
UniSTS entry: Chr 3 RH93226
UniSTS entry: Chr 3 STS-L19314
UniSTS entry: Chr 3 HES1
UniSTS entry: Chr 3 Hes1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_005524.3 Homo sapiens hairy and enhancer of split 1, (Drosophila) (HES1), mRNA PA
AK000415.1 Homo sapiens cDNA FLJ20408 fis, clone KAT01678 PA
CR541843.1 Homo sapiens full open reading frame cDNA clone RZPDo834C1232D for gene HES1, hairy and enhancer of split 1, (Drosophila); complete cds, without stopcodon P
AF264785.1 Homo sapiens hairy (HRY) mRNA, complete cds PA
BC005178.1 Homo sapiens, clone IMAGE:3951041, mRNA, partial cds A
AK300482.1 Homo sapiens cDNA FLJ57168 complete cds, moderately similar to Transcription factor HES-1
BC039152.1 Homo sapiens hairy and enhancer of split 1, (Drosophila), mRNA (cDNA clone MGC:21078 IMAGE:4749611), complete cds PA

EST sequences (10 of 425) [Show all sequences]

AA961411.1 Clone IMAGE:1597865 uncharacterized tissue 3' read A
AA907024.1 Clone IMAGE:1505754 mixed 3' read A
AA910411.1 Clone IMAGE:1505754 mixed 3' read
AA972325.1 Clone IMAGE:1582901 mixed 3' read A
AA904840.1 Clone IMAGE:1504645 mixed 3' read A
AA909670.1 Clone IMAGE:1544147 mixed 3' read
AI075723.1 Clone IMAGE:1676326 embryonic tissue 3' read A
R22228.1 Clone IMAGE:130900 placenta 3' read A
R22284.1 Clone IMAGE:130900 placenta 5' read
AI125639.1 Clone IMAGE:1737190 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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