> WEE1 homolog (S. pombe) (WEE1)
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UGID:169324     UniGene Hs.249441     Homo sapiens (human)   WEE1
WEE1 homolog (S. pombe) (WEE1)

Human protein-coding gene WEE1. Represented by 288 ESTs from 174 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 169324 - Hs.249441]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003381.1 WEE1 gene product H. sapiens 100.0 645
XP_521839.2 PREDICTED: wee1-like protein kinase isoform 2 P. troglodytes 99.8 645
XP_002808123.1 PREDICTED: LOW QUALITY PROTEIN: wee1-like protein kinase-like M. mulatta 99.7 645
XP_003910286.1 PREDICTED: wee1-like protein kinase isoform 1 P. anubis 99.5 645
XP_004016213.1 PREDICTED: Wee1 kinase O. aries 99.5 431
NP_033542.2 Wee1 gene product M. musculus 94.4 645
NP_001084186.1 wee1-like protein kinase 1-B X. laevis 85.2 575
NP_001005770.1 wee1 gene product D. rerio 77.5 595
NP_477035.1 wee, isoform A D. melanogaster 54.8 473
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
NP_001094675.1 WEE1 gene product B. taurus 99.0 421
XP_003123030.1 PREDICTED: wee1-like protein kinase S. scrofa 98.8 645

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pharynx; testis; uncharacterized tissue; bladder; embryonic tissue; brain; lymph node; uterus; placenta; mouth; kidney; connective tissue; bone marrow; adrenal gland; skin; mammary gland; prostate; eye; mixed; heart; lung; blood; liver; intestine; stomach; vascular; bone; thyroid; thymus; ascites; spleen; ovary; lymph; muscle; cervix; pancreas; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15.3-p15.1
UniSTS entry: Chr 11 RH18120
UniSTS entry: Chr 11 MARC_17360-17361:1021651098:1
UniSTS entry: Chr 11 WEE1 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BC051831.1 Homo sapiens WEE1 homolog (S. pombe), mRNA (cDNA clone MGC:60116 IMAGE:6147695), complete cds PA
AK122837.1 Homo sapiens cDNA FLJ16446 fis, clone BRAMY3010008, highly similar to Wee1-like protein kinase (EC 2.7.10.2) P
NM_003390.3 Homo sapiens WEE1 homolog (S. pombe) (WEE1), transcript variant 1, mRNA P
BC070052.1 Homo sapiens WEE1 homolog (S. pombe), mRNA (cDNA clone MGC:87158 IMAGE:30336707), complete cds PA
X62048.1 H.sapiens Wee1 hu gene P
U10564.1 Human CDK tyrosine 15-kinase WEE1Hu (Wee1Hu) mRNA, complete cds P
NM_001143976.1 Homo sapiens WEE1 homolog (S. pombe) (WEE1), transcript variant 2, mRNA P

EST sequences (10 of 288) [Show all sequences]

AI061145.1 Clone IMAGE:1700699 kidney 3' read A
CB047170.1 Clone IMAGE:3253178 kidney 3' read A
BX117974.1 Clone IMAGp998F06340_;_IMAGE:183173 mammary gland
BX091938.1 Clone IMAGp998L194863_;_IMAGE:1979298 stomach A
R25642.1 Clone IMAGE:132850 placenta 3' read A
R27487.1 Clone IMAGE:132850 placenta 5' read
AI204207.1 Clone IMAGE:1754122 testis 3' read A
CB157856.1 Clone L18POOL1n1-5-A08 liver 5' read
CB106654.1 Clone L3SNU475-7-A09 liver 5' read P
CB113055.1 Clone L6ChoCK0-8-G04 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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