> POU class 5 homeobox 1 (POU5F1)
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UGID:169248     UniGene Hs.249184     Homo sapiens (human)   POU5F1 Order cDNA clone, Links
POU class 5 homeobox 1 (POU5F1)

Human protein-coding gene POU5F1. Represented by 127 ESTs from 26 cDNA libraries. EST representation biased toward embryonic tissue; blastocyst. Corresponds to 3 reference sequences (different isoforms). [UniGene 169248 - Hs.249184]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001238970.1 POU domain, class 5, transcription factor 1 P. troglodytes 100.0 359
NP_002692.2 POU5F1 gene product H. sapiens 100.0 359
XP_003897368.1 PREDICTED: POU domain, class 5, transcription factor 1 P. anubis 99.7 359
NP_038661.2 Pou5f1 gene product M. musculus 88.6 351
NP_497728.2 Protein BEN-1 C. elegans 83.5 139
NP_193821.1 tubulin beta-9 chain A. thaliana 81.3 139
XP_957669.2 tubulin beta chain N. crassa 77.0 139
XP_001693997.1 beta tubulin 2 C. reinhardtii 75.5 155
NP_116616.1 Tub2p S. cerevisiae 66.2 145
NP_571187.1 pou5f1 gene product D. rerio 60.8 268
NP_523948.1 ventral veins lacking, isoform A D. melanogaster 60.1 188
NP_001081583.1 POU class V protein oct-60 X. laevis 57.0 256
Other hits (2 of 66) [Show all]SpeciesId(%)Len(aa)
NP_001108427.1 POU5F1 gene product M. mulatta 98.9 359
XP_001490158.1 PREDICTED: POU domain, class 5, transcription factor 1-like E. caballus 96.7 359

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: embryonic tissue [show more like this]
blastocyst [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; testis; uncharacterized tissue; lung; stomach; ovary; mammary gland; uterus; brain; liver
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.31
UniSTS entry: Chr 3 POU5F1
UniSTS entry: Chr 6 SHGC-12693
UniSTS entry: Chr 1 D16S325
UniSTS entry: Chr 1 D10S16
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (43)

NM_002701.4 Homo sapiens POU class 5 homeobox 1 (POU5F1), transcript variant 1, mRNA P
NM_203289.4 Homo sapiens POU class 5 homeobox 1 (POU5F1), transcript variant 2, mRNA PA
BC069246.1 Homo sapiens POU class 5 homeobox 1, mRNA (cDNA clone IMAGE:6578897), with apparent retained intron PA
DQ486517.1 Homo sapiens POU domain transcription factor Oct-3 alternative transcript 6.4 (POU5F1) pseudogene mRNA, complete sequence, alternatively spliced PA
DQ486516.1 Homo sapiens POU domain transcription factor Oct-3 alternative transcript 6.3 (POU5F1) pseudogene mRNA, complete sequence, alternatively spliced PA
DQ486515.1 Homo sapiens POU domain transcription factor Oct-3 alternative transcript 6.2 (POU5F1) pseudogene mRNA, complete sequence, alternatively spliced PA
BC117435.1 Homo sapiens POU class 5 homeobox 1, mRNA (cDNA clone MGC:151044 IMAGE:40125986), complete cds P
BC117437.1 Homo sapiens POU class 5 homeobox 1, mRNA (cDNA clone MGC:151046 IMAGE:40125988), complete cds P
BC020712.1 Homo sapiens POU domain, class 5, transcription factor 1, mRNA (cDNA clone IMAGE:4717277) PA
AM851126.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 12
AM851125.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 11
AM851124.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 10
AM851123.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 9
AM851122.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 8
AM851121.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 7
AM851120.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 6 P
AM851119.1 Homo sapiens mRNA for putative truncated POU domain class 5 transcription factor 1 (POU5F1 gene), clone 5 P
AM851118.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 4 P
AM851117.1 Homo sapiens mRNA for putative truncated POU domain class 5 transcription factor 1 (POU5F1 gene), clone 3 P
AM851116.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 2 P
AM851115.1 Homo sapiens partial mRNA for POU domain class 5 transcription factor 1 (POU5F1 gene), clone 1 P
FM177963.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-09 P
FM177962.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-08 P
FM177961.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-06 P
FM177960.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-05 P
FM177959.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-04 P
FM177958.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-03_AS P
FM177957.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-02_AS P
FM177956.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-01 P
FM177955.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-2 P
FM177954.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-1 P
FM177953.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone ARO0003060 P
FM177952.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone ARO0003059 P
FM177951.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone ARO0003057_AS P
FM177968.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone UVSC-TAKA-01 P
FM177967.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone BM-TAKA-28_AS P
FM177966.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone BM-TAKA-17_AS P
FM177965.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone BM1819 P
FM177964.1 Homo sapiens partial mRNA for POU class 5 homeobox 1 (POU5F1 gene), clone EC-TAKA-10_AS P
S81255.1 OCT4=transcriptional regulator [human, tripronuclear ova and embryos, mRNA Partial, 225 nt]
Z11898.1 H.sapiens OTF3 mRNA encoding octamer binding protein 3A P
Z11899.1 H.sapiens OTF3 mRNA encoding octamer binding protein 3B P
NM_001173531.1 Homo sapiens POU class 5 homeobox 1 (POU5F1), transcript variant 3, mRNA PA

EST sequences (10 of 127) [Show all sequences]

AA961784.1 Clone IMAGE:1598385 uncharacterized tissue 3' read A
AA961892.1 Clone IMAGE:1598718 uncharacterized tissue 3' read A
AA968768.1 Clone IMAGE:1597456 uncharacterized tissue 3' read
AA968769.1 Clone IMAGE:1597458 uncharacterized tissue 3' read A
AA991942.1 Clone IMAGE:1613494 uncharacterized tissue 3' read A
AA996055.1 Clone IMAGE:1607129 mammary gland 3' read A
CB146469.1 Clone L11SNU354s1-7-C12 liver 5' read P
AI798436.1 Clone IMAGE:2220269 ovary 3' read A
AI811039.1 Clone IMAGE:2217215 ovary 3' read A
CD048028.1 embryonic tissue 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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