Adrenoceptor alpha 2A (ADRA2A)

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UGID:169241 UniGene Hs.249159 Homo sapiens (human) ADRA2A

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Adrenoceptor alpha 2A (ADRA2A)

Human protein-coding gene ADRA2A. Represented by 76 ESTs from 42 cDNA libraries. Corresponds to reference sequence NM_000681.3. [UniGene 169241 - Hs.249159]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_000672.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ADRA2A gene product	H. sapiens	100.0	464
NP_031443.4 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Adra2a gene product	M. musculus	93.1	464
NP_997520.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	adra2a gene product	D. rerio	64.9	384
Other hits (2 of 25) [Show all]		Species	Id(%)	Len(aa)
XP_003312813.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: alpha-2A adrenergic receptor	P. troglodytes	99.1	464
XP_001087738.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: alpha-2A adrenergic receptor	M. mulatta	97.2	464

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; pancreas; uncharacterized tissue; intestine; stomach; cervix; kidney; adrenal gland; eye; placenta; heart; prostate; ear; ovary; uterus; mixed; testis; connective tissue; mammary gland; nerve; embryonic tissue

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	10
Map position:	10q25.2
UniSTS entry:	Chr 10	D10S1861	[Map Viewer]
UniSTS entry:	Chr 10	RH93859
UniSTS entry:	Chr 10	STS-AA040321	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

BC050414.1	Homo sapiens adrenergic, alpha-2A-, receptor, mRNA (cDNA clone MGC:54083 IMAGE:6198830), complete cds	PA
NM_000681.3	Homo sapiens adrenoceptor alpha 2A (ADRA2A), mRNA	PA
AF284095.1	Homo sapiens alpha-2A adrenergic receptor mRNA, complete cds	P
BC035047.1	Homo sapiens adrenergic, alpha-2A-, receptor, mRNA (cDNA clone MGC:41760 IMAGE:5266354), complete cds	PA

EST sequences (10 of 76) [Show all sequences]

R17967.1	Clone IMAGE:32484	brain	5' read
AI131333.1	Clone IMAGE:1709954	heart	3' read	A
CB045318.1	Clone IMAGE:3218440	intestine	5' read	P
CB045497.1	Clone IMAGE:3218479	intestine	3' read	A
CB045498.1	Clone IMAGE:3218479	intestine	5' read
AI147682.1	Clone IMAGE:1697527	uterus	3' read	A
R27599.1	Clone IMAGE:134559	placenta	3' read	A
R27698.1	Clone IMAGE:134559	placenta	5' read
AI572103.1	Clone IMAGE:2223979	pancreas	3' read
AI597708.1	Clone IMAGE:2254605	prostate	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria