Oncostatin M (OSM)

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UGID:169062 UniGene Hs.248156 Homo sapiens (human) OSM

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Oncostatin M (OSM)

Human protein-coding gene OSM. Represented by 29 ESTs from 19 cDNA libraries. Corresponds to reference sequence NM_020530.4. [UniGene 169062 - Hs.248156]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_065391.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	OSM gene product	H. sapiens	100.0	251
XP_001136178.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: oncostatin-M	P. troglodytes	99.6	251
NP_001013383.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Osm gene product	M. musculus	49.1	222
Other hits (2 of 8) [Show all]		Species	Id(%)	Len(aa)
XP_001110148.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: oncostatin-M-like	M. mulatta	92.5	251
XP_003905465.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: oncostatin-M	P. anubis	92.1	251

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	lung; blood; mixed; intestine; kidney; uncharacterized tissue; thymus; ovary

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	22
Map position:	22q12.2
UniSTS entry:	Chr 22	GDB:452636
UniSTS entry:	Chr 22	GDB:194718
UniSTS entry:	Chr 22	STS-M27288	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

CR456534.1	Homo sapiens OSM full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.OSM.V6)	P
CR541703.1	Homo sapiens full open reading frame cDNA clone RZPDo834E0828D for gene OSM, oncostatin M; complete cds, without stopcodon	P
NM_020530.4	Homo sapiens oncostatin M (OSM), mRNA	PA
BC011589.1	Homo sapiens oncostatin M, mRNA (cDNA clone MGC:20461 IMAGE:4548943), complete cds	PA
AB451493.1	Homo sapiens OSM mRNA for oncostatin M precursor, partial cds, clone: FLJ80003DABN	P

EST sequences (10 of 29) [Show all sequences]

AI079327.1	Clone IMAGE:1677457	mixed	3' read
AI476474.1	Clone IMAGE:2156806	intestine	3' read	A
AI696470.1	Clone IMAGE:2273067	lung	3' read
BX280034.1	Clone IMAGp998L024258_;_IMAGE:1677457	mixed
CD365006.1	Clone UI-H-FT2-bjn-g-02-0-UI	lung	3' read	A
CD365429.1	Clone UI-H-FT2-bjj-l-17-0-UI	lung	3' read	A
CD365505.1	Clone UI-H-FT2-bjj-l-10-0-UI	lung	3' read	A
CD365526.1	Clone UI-H-FT2-bjj-p-08-0-UI	lung	3' read	A
CD366754.1	Clone UI-H-FT2-bjo-f-04-0-UI	lung	3' read	A
CD368803.1	Clone UI-H-FT1-bjx-c-08-0-UI	lung	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria