> 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled (HTR1A)
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UGID:168996     UniGene Hs.247940     Homo sapiens (human)   HTR1A Order cDNA clone, Links
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled (HTR1A)

Human protein-coding gene HTR1A. Represented by 53 ESTs from 14 cDNA libraries. EST representation biased toward brain; normal; fetus. Corresponds to reference sequence NM_000524.3. [UniGene 168996 - Hs.247940]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000515.2 HTR1A gene product H. sapiens 100.0 421
NP_001129094.1 5-hydroxytryptamine receptor 1A P. troglodytes 99.8 421
NP_032334.2 Htr1a gene product M. musculus 95.0 420
NP_001116793.1 htr1aa gene product D. rerio 85.8 393
NP_001079299.1 5-hydroxytryptamine receptor 1A X. laevis 84.5 381
NP_001163201.1 serotonin receptor 1B, isoform C D. melanogaster 49.8 197
NP_497452.1 Protein SER-4 C. elegans 47.0 183
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003899768.1 PREDICTED: 5-hydroxytryptamine receptor 1A isoform 1 P. anubis 99.3 421
XP_001083407.1 PREDICTED: 5-hydroxytryptamine receptor 1A M. mulatta 99.0 420

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: brain [show more like this]
normal [show more like this]
fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q11.2-q13
UniSTS entry: Chr 5 HTR1A
UniSTS entry: Chr 5 RH70818
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_000524.3 Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled (HTR1A), mRNA PA
BC069159.1 Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, mRNA (cDNA clone MGC:95445 IMAGE:7217020), complete cds P
AK291429.1 Homo sapiens cDNA FLJ75939 complete cds, highly similar to Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A), mRNA P
AK314187.1 Homo sapiens cDNA, FLJ94910 P
AK311460.1 Homo sapiens cDNA, FLJ18502
AF498978.1 Homo sapiens 5-hydroxytryptamine receptor 1A (HTR1A) mRNA, complete cds P
S64045.1 5HT1a=5-hydroxytryptamine receptor {transmembrane regions 5 and 6} [human, T cells, mRNA Partial, 503 nt] P
BC136263.1 Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, mRNA (cDNA clone MGC:167873 IMAGE:9020250), complete cds P

EST sequences (10 of 53) [Show all sequences]

CD608771.1 uncharacterized tissue P
CD608772.1 uncharacterized tissue
CD608773.1 uncharacterized tissue
CD608774.1 uncharacterized tissue P
CD608775.1 uncharacterized tissue
CD608776.1 uncharacterized tissue
CO959564.1 Clone IMAGE:7389775 uncharacterized tissue 5' read P
DR000960.1 Clone TC119816 brain 5' read P
DA195991.1 Clone BRAMY4001562 brain 5' read P
DA313513.1 Clone BRHIP3003067 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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