> Ras homolog family member A (RHOA)
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UGID:168897     UniGene Hs.247077     Homo sapiens (human)   RHOA Order cDNA clone, Links
Ras homolog family member A (RHOA)

Human protein-coding gene RHOA. Represented by 3265 ESTs from 669 cDNA libraries. Corresponds to reference sequence NM_001664.2. [UniGene 168897 - Hs.247077]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_058082.2 Rhoa gene product M. musculus 100.0 192
NP_476473.1 Rhoa gene product R. norvegicus 100.0 192
XP_001368015.1 PREDICTED: transforming protein RhoA-like M. domestica 100.0 192
XP_003217600.1 PREDICTED: transforming protein RhoA-like A. carolinensis 100.0 192
NP_001232551.1 LOC100190386 gene product T. guttata 100.0 192
NP_990035.1 RHOA gene product G. gallus 100.0 192
XP_003210049.1 PREDICTED: transforming protein RhoA-like M. gallopavo 100.0 192
XP_003894479.1 PREDICTED: transforming protein RhoA P. anubis 100.0 192
XP_001163851.3 PREDICTED: transforming protein RhoA isoform 4 P. troglodytes 100.0 192
NP_001655.1 RHOA gene product H. sapiens 100.0 192
NP_001003273.2 RHOA gene product C. lupus familiaris 100.0 192
XP_001497809.1 PREDICTED: transforming protein RhoA-like E. caballus 100.0 192
NP_001231366.1 ras homolog gene family, member A S. scrofa 100.0 192
NP_788818.1 RHOA gene product B. taurus 100.0 192
NP_001155347.1 RHOA gene product O. aries 100.0 192
XP_002713474.1 PREDICTED: ras homolog gene family, member A O. cuniculus 100.0 192
NP_998515.1 rhoac gene product D. rerio 99.5 192
NP_001079729.1 ras homolog family member A X. laevis 99.5 192
NP_477098.1 Rho1, isoform A D. melanogaster 96.9 191
NP_502959.1 Protein RHO-1 C. elegans 96.3 191
NP_015491.1 Rho1p S. cerevisiae 82.7 201
XP_956761.2 GTP-binding protein RHO-1 protein N. crassa 81.9 192
NP_190698.1 Rac-like GTP-binding protein ARAC11 A. thaliana 57.4 194
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
XP_003973278.1 PREDICTED: transforming protein RhoA-like T. rubripes 99.5 192
NP_001187623.1 rho-related gtp-binding protein rhoc I. punctatus 99.5 192

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; skin; prostate; testis; placenta; mixed; embryonic tissue; uterus; connective tissue; intestine; uncharacterized tissue; eye; kidney; liver; blood; pancreas; bone; cervix; ovary; mammary gland; lymph node; stomach; bone marrow; thymus; heart; muscle; pharynx; ascites; lymph; vascular; parathyroid; tonsil; thyroid; epididymis; bladder; adrenal gland; nerve; pituitary gland; ganglia; esophagus; spleen; salivary gland; amniotic fluid; adipose tissue; ear; larynx; mouth; trachea; pineal gland; spinal cord; bronchus; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p21.3
UniSTS entry: Chr 3 WI-18922 [Map Viewer]
UniSTS entry: Chr 3 RH91501
UniSTS entry: Chr 3 A004T30 [Map Viewer]
UniSTS entry: Chr 3 GDB:181197
UniSTS entry: Chr 3 G60181
UniSTS entry: Chr 3 D3S1330E
UniSTS entry: Chr 15 Rnu2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BX647063.1 Homo sapiens mRNA; cDNA DKFZp686F10192 (from clone DKFZp686F10192); complete cds PA
AK130808.1 Homo sapiens cDNA FLJ27298 fis, clone TMS04601, highly similar to Transforming protein RhoA P
AK130066.1 Homo sapiens cDNA FLJ26556 fis, clone LNF01953, highly similar to Transforming protein RhoA P
L09159.1 Homo sapiens RHOA proto-oncogene multi-drug-resistance protein mRNA, 3' end P
BT019870.1 Homo sapiens ras homolog gene family, member A mRNA, complete cds P
AK222556.1 Homo sapiens mRNA for ras homolog gene family, member A variant, clone: adSU01332 PA
NM_001664.2 Homo sapiens ras homolog family member A (RHOA), mRNA PA
L25080.1 Homo sapiens GTP-binding protein (rhoA) mRNA, complete cds PA
BC000946.3 Homo sapiens ras homolog gene family, member A, mRNA (cDNA clone IMAGE:3449658), partial cds PA
BC001360.2 Homo sapiens ras homolog gene family, member A, mRNA (cDNA clone MGC:2330 IMAGE:3051460), complete cds PA
BC005976.1 Homo sapiens ras homolog gene family, member A, mRNA (cDNA clone MGC:14663 IMAGE:4102976), complete cds PA
AK307220.1 Homo sapiens cDNA, FLJ97168 P
AF498970.1 Homo sapiens small GTP binding protein RhoA (ARHA) mRNA, complete cds P
AK296654.1 Homo sapiens cDNA FLJ57740 complete cds, highly similar to Transforming protein RhoA precursor P
X05026.1 Human rho mRNA (clone 12) P

EST sequences (10 of 3265) [Show all sequences]

AA970432.1 Clone IMAGE:1576395 intestine 3' read A
R15821.1 Clone IMAGE:53006 brain 3' read A
AA971422.1 Clone IMAGE:1584322 lung 3' read A
R14876.1 Clone IMAGE:129529 mixed 3' read A
AA983498.1 Clone IMAGE:1598366 uncharacterized tissue 3' read
AA983499.1 Clone IMAGE:1598368 uncharacterized tissue 3' read A
AA988980.1 Clone IMAGE:1602843 lung 3' read P
AA988983.1 Clone IMAGE:1602855 lung 3' read
AA991887.1 Clone IMAGE:1611218 uncharacterized tissue 3' read A
AI001219.1 Clone IMAGE:1613247 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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