> Structural maintenance of chromosomes 3 (SMC3)
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UGID:134858     UniGene Hs.24485     Homo sapiens (human)   SMC3 Order cDNA clone, Links
Structural maintenance of chromosomes 3 (SMC3)

Human protein-coding gene SMC3. Represented by 319 ESTs from 157 cDNA libraries. Corresponds to reference sequence NM_005445.3. [UniGene 134858 - Hs.24485]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_031816.2 Smc3 gene product M. musculus 100.0 1216
NP_113771.2 Smc3 gene product R. norvegicus 100.0 1216
XP_003904298.1 PREDICTED: LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 3 P. anubis 100.0 1216
XP_508031.3 PREDICTED: structural maintenance of chromosomes protein 3 P. troglodytes 100.0 1216
NP_005436.1 SMC3 gene product H. sapiens 100.0 1216
XP_851818.2 PREDICTED: structural maintenance of chromosomes protein 3 isoform 2 C. lupus familiaris 100.0 1216
XP_001496837.1 PREDICTED: structural maintenance of chromosomes protein 3 E. caballus 100.0 1216
XP_001926614.1 PREDICTED: structural maintenance of chromosomes protein 3 S. scrofa 100.0 1216
XP_004020238.1 PREDICTED: structural maintenance of chromosomes protein 3 isoform 1 O. aries 100.0 1216
XP_002718785.1 PREDICTED: structural maintenance of chromosomes 3 O. cuniculus 100.0 1216
XP_002805863.1 PREDICTED: structural maintenance of chromosomes protein 3-like M. mulatta 99.9 1203
NP_776720.1 SMC3 gene product B. taurus 99.8 1217
XP_001368555.1 PREDICTED: structural maintenance of chromosomes protein 3 M. domestica 99.8 1216
XP_002197776.1 PREDICTED: structural maintenance of chromosomes protein 3 T. guttata 99.8 1216
NP_989848.1 SMC3 gene product G. gallus 99.8 1216
XP_003208202.1 PREDICTED: structural maintenance of chromosomes protein 3-like M. gallopavo 99.7 1204
NP_001083742.1 structural maintenance of chromosomes 3 X. laevis 98.6 1216
NP_999854.1 smc3 gene product D. rerio 97.5 1215
NP_523374.2 Chromosome-associated protein, isoform A D. melanogaster 65.8 1199
NP_001255119.1 Protein SMC-3, isoform c C. elegans 64.4 328
NP_001077968.1 structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) A. thaliana 58.5 1202
XP_957879.2 hypothetical protein NCU07554 N. crassa 54.1 1111
XP_001698278.1 structural maintenance of chromosomes protein 3 C. reinhardtii 53.0 1120
NP_012461.1 Smc3p S. cerevisiae 49.4 1198
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_001512851.2 PREDICTED: structural maintenance of chromosomes protein 3-like O. anatinus 99.4 1240
XP_003218572.1 PREDICTED: LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 3-like A. carolinensis 99.2 1216

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; embryonic tissue; kidney; prostate; pancreas; blood; liver; mixed; placenta; uterus; intestine; pharynx; bone marrow; pituitary gland; skin; ear; connective tissue; ovary; lung; lymph; muscle; eye; mouth; stomach; thymus; lymph node; bladder; trachea; mammary gland; adipose tissue; bone; adrenal gland; vascular; ascites; larynx; heart; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q25
UniSTS entry: Chr 10 SMC3-1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF020043.1 Homo sapiens chromosome-associated polypeptide (HCAP) mRNA, complete cds PA
BC047324.1 Homo sapiens structural maintenance of chromosomes 3, mRNA (cDNA clone MGC:54230 IMAGE:5493263), complete cds PA
NM_005445.3 Homo sapiens structural maintenance of chromosomes 3 (SMC3), mRNA PA
AK289771.1 Homo sapiens cDNA FLJ75104 complete cds, highly similar to Homo sapiens chondroitin sulfate proteoglycan 6 (bamacan) (CSPG6),mRNA P
AK315845.1 Homo sapiens cDNA, FLJ79494 complete cds, highly similar to Structural maintenance of chromosome 3 P
AF067163.1 Homo sapiens bamacan homolog mRNA, complete cds PA
AL360194.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 432401 A
AJ005015.1 Homo sapiens mRNA for putative SMC-like protein, partial PA

EST sequences (10 of 319) [Show all sequences]

AI016991.1 Clone IMAGE:1635242 kidney 3' read P
AI093931.1 Clone IMAGE:1688004 mixed 3' read
AI123791.1 Clone IMAGE:1567203 mixed 3' read A
AI087260.1 Clone IMAGE:1681017 skin 3' read PA
BX114285.1 Clone IMAGp998L071204_;_IMAGE:504726 uterus P
AI207305.1 Clone IMAGE:1759172 placenta 3' read A
CB143485.1 Clone L16HLK3-16-H01 liver 5' read P
CB146383.1 Clone L16HLK3-8-B08 liver 5' read A
CB158679.1 Clone L18POOL1n1-13-B02 liver 5' read P
CB134667.1 Clone L14ChoiCK0-15-F06 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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