> SRY (sex determining region Y)-box 8 (SOX8)
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UGID:168292     UniGene Hs.243678     Homo sapiens (human)   SOX8 Order cDNA clone, Links
SRY (sex determining region Y)-box 8 (SOX8)

Human protein-coding gene SOX8. Represented by 122 ESTs from 38 cDNA libraries. EST representation biased toward glioma. Corresponds to reference sequence NM_014587.3. [UniGene 168292 - Hs.243678]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055402.2 SOX8 gene product H. sapiens 100.0 445
NP_035577.1 Sox8 gene product M. musculus 83.6 463
NP_001083964.1 transcription factor Sox-8 X. laevis 71.9 458
XP_002667667.2 PREDICTED: transcription factor SOX-8-like D. rerio 59.5 384
NP_651839.1 Sox100B D. melanogaster 52.9 136
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_510724.3 PREDICTED: transcription factor SOX-8 P. troglodytes 99.5 360
XP_003916359.1 PREDICTED: transcription factor SOX-8 P. anubis 97.3 445

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: glioma [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; nerve; mammary gland; eye; mixed; uncharacterized tissue; prostate; embryonic tissue; ganglia; heart; testis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13.3
UniSTS entry: Chr 16 STS-H16586
UniSTS entry: Chr 16 Sox9
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

AF226675.1 Homo sapiens transcription factor SOX8 mRNA, complete cds P
AF164104.1 Homo sapiens transcription factor SOX8 (SOX8) mRNA, partial cds P
NM_014587.3 Homo sapiens SRY (sex determining region Y)-box 8 (SOX8), mRNA PA
BC031797.1 Homo sapiens SRY (sex determining region Y)-box 8, mRNA (cDNA clone MGC:24837 IMAGE:4937883), complete cds PA

EST sequences (10 of 122) [Show all sequences]

R15122.1 Clone IMAGE:29626 brain 5' read
AI151033.1 Clone IMAGE:1704793 brain 3' read A
AI263761.1 Clone IMAGE:1856082 mixed 3' read A
CB156566.1 Clone B2N807043-18-D06 brain 5' read A
AA904134.1 Clone IMAGE:1440399 ganglia 3' read A
AI333191.1 Clone IMAGE:1931640 mixed 3' read A
AI341639.1 Clone IMAGE:1939126 embryonic tissue 3' read A
AI421997.1 Clone IMAGE:2099166 brain 3' read A
AI459734.1 Clone IMAGE:1955565 brain 3' read
AI470991.1 Clone IMAGE:2106436 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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