Diacylglycerol kinase, iota (DGKI)

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UGID:168155 UniGene Hs.242947 Homo sapiens (human) DGKI

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Diacylglycerol kinase, iota (DGKI)

Human protein-coding gene DGKI. Represented by 34 ESTs from 25 cDNA libraries. Corresponds to reference sequence NM_004717.2. [UniGene 168155 - Hs.242947]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_004708.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	DGKI gene product	H. sapiens	100.0	1064
XP_001147695.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: diacylglycerol kinase iota	P. troglodytes	99.8	1065
XP_001107030.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: diacylglycerol kinase iota	M. mulatta	99.6	1065
NP_001074675.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	diacylglycerol kinase iota	M. musculus	93.2	1070
XP_001922445.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: diacylglycerol kinase zeta	D. rerio	72.3	988
NP_001036264.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	retinal degeneration A, isoform E	D. melanogaster	58.3	235
NP_495301.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein DGK-5	C. elegans	51.7	207
Other hits (2 of 35) [Show all]		Species	Id(%)	Len(aa)
XP_003896699.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: diacylglycerol kinase iota	P. anubis	98.7	909
XP_002687107.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: diacylglycerol kinase iota	B. taurus	97.1	1044

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; testis; embryonic tissue; eye; placenta; skin; connective tissue; mixed; kidney; liver; heart

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	7
Map position:	7q32.3-q33
UniSTS entry:	Chr 7	RH66737
UniSTS entry:	Chr 7	DGKI_589
UniSTS entry:	Chr 7	SHGC-34310

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

NM_004717.2	Homo sapiens diacylglycerol kinase, iota (DGKI), mRNA	P
AB209167.1	Homo sapiens mRNA for diacylglycerol kinase, iota variant protein	P
AK091081.1	Homo sapiens cDNA FLJ33762 fis, clone BRCOC2000152, highly similar to Diacylglycerol kinase iota (EC 2.7.1.107)	P

EST sequences (10 of 34) [Show all sequences]

AA904515.1	Clone IMAGE:1524578	mixed	3' read
BX095830.1	Clone IMAGp998F24174_;_IMAGE:41824	brain
R54194.1	Clone IMAGE:41824	brain	5' read
R54195.1	Clone IMAGE:41824	brain	3' read
AL049128.1	Clone DKFZp434D0919	testis
H00453.1	Clone IMAGE:149671	placenta	3' read
CN282692.1		embryonic tissue	5' read	P
BP222921.1	Clone COR05267	skin	5' read	P
H37913.1	Clone IMAGE:190969	eye	3' read	P
DR002813.1	Clone TC121406	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria