> Kallikrein B, plasma (Fletcher factor) 1 (KLKB1)
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UGID:167654     UniGene Hs.237642     Homo sapiens (human)   KLKB1 Order cDNA clone, Links
Kallikrein B, plasma (Fletcher factor) 1 (KLKB1)

Human protein-coding gene KLKB1. Represented by 60 ESTs from 32 cDNA libraries. EST representation biased toward liver tumor. Corresponds to reference sequence NM_000892.3. [UniGene 167654 - Hs.237642]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000883.2 KLKB1 gene product H. sapiens 100.0 637
NP_032481.2 Klkb1 gene product M. musculus 78.8 637
NP_001086768.1 plasma kallikrein B1 precursor X. laevis 50.6 628
NP_001071206.1 tmprss4a gene product D. rerio 46.8 201
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_002804322.1 PREDICTED: plasma kallikrein-like M. mulatta 95.8 622
XP_003899480.1 PREDICTED: plasma kallikrein P. anubis 95.8 637

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: liver tumor [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; mixed; eye; brain; pancreas; embryonic tissue; kidney; mammary gland; heart; stomach; connective tissue; intestine; thymus; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q35
UniSTS entry: Chr 4 D4S3127 [Map Viewer]
UniSTS entry: Chr 4 STS-M13143 [Map Viewer]
UniSTS entry: Chr 4 SHGC4-1080
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_000892.3 Homo sapiens kallikrein B, plasma (Fletcher factor) 1 (KLKB1), mRNA P
M13143.2 Homo sapiens plasma prekallikrein (KLK3) mRNA, complete cds P
BC117351.1 Homo sapiens kallikrein B, plasma (Fletcher factor) 1, mRNA (cDNA clone MGC:150960 IMAGE:40125902), complete cds P
BC117349.1 Homo sapiens kallikrein B, plasma (Fletcher factor) 1, mRNA (cDNA clone MGC:150958 IMAGE:40125900), complete cds P
AK292624.1 Homo sapiens cDNA FLJ77744 complete cds, highly similar to Homo sapiens kallikrein B, plasma (Fletcher factor) 1 (KLKB1), mRNA PA
AK313378.1 Homo sapiens cDNA, FLJ93910, Homo sapiens kallikrein B, plasma (Fletcher factor) 1 (KLKB1),mRNA P
AK297672.1 Homo sapiens cDNA FLJ51250 complete cds, highly similar to Plasma kallikrein precursor (EC 3.4.21.34) PA
BC143911.1 Homo sapiens cDNA clone IMAGE:9052429, with apparent retained intron P

EST sequences (10 of 60) [Show all sequences]

CB161814.1 Clone L17N670205n1-50-D02 liver 5' read P
CB163561.1 Clone L17N670205n1-32-G03 liver 5' read P
CB164461.1 Clone L17N670205n1-48-B07 liver 5' read P
CB161250.1 Clone L17N670205n1-20-A12 liver 5' read P
CB162532.1 Clone L17N670205n1-27-A08 liver 5' read P
CB116942.1 Clone L7N800102-4-B07 liver 5' read P
AI247906.1 Clone IMAGE:1848909 mixed 3' read A
BX119761.1 Clone IMAGp998A23530_;_IMAGE:245662 mixed P
AI670809.1 Clone IMAGE:2297114 kidney 3' read PA
AI798892.1 Clone IMAGE:2348716 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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