> Acetyl-CoA acetyltransferase 1 (ACAT1)
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UGID:166937     UniGene Hs.232375     Homo sapiens (human)   ACAT1 Links
Acetyl-CoA acetyltransferase 1 (ACAT1)

Human protein-coding gene ACAT1. Represented by 152 ESTs from 109 cDNA libraries. Corresponds to reference sequence NM_000019.3. [UniGene 166937 - Hs.232375]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_508738.2 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial P. troglodytes 100.0 426
NP_000010.1 ACAT1 gene product H. sapiens 100.0 426
XP_001103928.1 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial M. mulatta 99.5 426
XP_003910695.1 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial P. anubis 99.5 426
NP_659033.1 Acat1 gene product M. musculus 89.9 423
NP_001003746.1 acat1 gene product D. rerio 83.0 411
NP_001086028.1 acetyl-CoA acetyltransferase B, mitochondrial precursor X. laevis 80.9 417
NP_572414.1 CG10932 D. melanogaster 69.5 406
NP_495455.2 Protein KAT-1 C. elegans 57.2 385
NP_851154.1 acetyl-CoA acetyltransferase, cytosolic 1 A. thaliana 56.1 391
XP_964434.2 acetyl-CoA acetyltransferase N. crassa 53.4 399
XP_001694888.1 predicted protein C. reinhardtii 51.9 393
NP_015297.1 acetyl-CoA C-acetyltransferase S. cerevisiae 48.5 395
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_004016590.1 PREDICTED: acetyl-CoA acetyltransferase, mitochondrial, partial O. aries 95.9 412
NP_001039540.1 ACAT1 gene product B. taurus 94.8 421

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; stomach; muscle; intestine; uncharacterized tissue; embryonic tissue; heart; mammary gland; uterus; mixed; placenta; lung; bladder; mouth; ovary; blood; esophagus; eye; adrenal gland; testis; kidney; liver; prostate; adipose tissue; connective tissue; skin; ascites; larynx; ganglia; pancreas; umbilical cord; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q22.3
UniSTS entry: Chr 11 D11S4336 [Map Viewer]
UniSTS entry: Chr 11 D11S2051
UniSTS entry: Chr 11 D11S2241E
UniSTS entry: GDB:555481
UniSTS entry: Chr 11 STS-AA010069 [Map Viewer]
UniSTS entry: GDB:555487
UniSTS entry: GDB:555490
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

S70578.1 acetoacetyl-coenzyme A thiolase {Q272STOP, exon 8} [human, GK07, Pre-mRNA Partial Mutant, 100 nt]
NM_000019.3 Homo sapiens acetyl-CoA acetyltransferase 1 (ACAT1), nuclear gene encoding mitochondrial protein, mRNA PA
BC010942.1 Homo sapiens acetyl-Coenzyme A acetyltransferase 1, mRNA (cDNA clone IMAGE:4278329), complete cds PA
AK312574.1 Homo sapiens cDNA, FLJ92949, Homo sapiens acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (ACAT1), nuclear gene encoding mitochondrial protein, mRNA P
D90228.1 Homo sapiens mRNA for mitochondrial acetoacetyl-CoA thiolase precursor, complete cds P
AF086561.1 Homo sapiens full length insert cDNA clone ZE16B08

EST sequences (10 of 152) [Show all sequences]

AI139512.1 Clone IMAGE:1710629 uterus 3' read P
AI202672.1 Clone IMAGE:1944363 prostate 3' read
AI471445.1 Clone IMAGE:2156283 intestine 3' read P
AI567965.1 Clone IMAGE:2215704 ovary 3' read
AI654154.1 Clone IMAGE:2283665 kidney 3' read A
F26363.1 Clone s4000053C06 muscle A
F27643.1 Clone s4000011A03 muscle P
F28457.1 Clone s3000016E12 muscle P
F28477.1 Clone s3000016H12 muscle
F36678.1 Clone sH5-000018-0/H11 muscle


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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