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UGID:131190     UniGene Hs.2250     Homo sapiens (human)   LIF
Leukemia inhibitory factor (cholinergic differentiation factor) (LIF)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001108593.1 PREDICTED: similar to Leukemia inhibitory factor precursor (LIF) (Differentiation-stimulating factor) (D factor) (Melanoma-derived LPL inhibitor) (MLPLI) (Emfilermin) M. mulatta 100.0 201
NP_002300.1 leukemia inhibitory factor (cholinergic differentiation factor) precursor H. sapiens 100.0 201
XP_001140005.1 PREDICTED: similar to myeloid leukemia-inhibitory factor (AA at 10) P. troglodytes 100.0 157
NP_032527.1 leukemia inhibitory factor isoform a M. musculus 84.7 202

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: embryoid body [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; pancreas; uncharacterized tissue; lung; pharynx; skin; mouth; uterus; intestine; stomach; mammary gland; brain; placenta; amniotic fluid; kidney; bone marrow; trachea; eye; mixed; muscle; connective tissue; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q12.2
UniSTS entry: Chr 22 SHGC-7772
UniSTS entry: Chr 22 GDB:624823
UniSTS entry: Chr 22 GDB:625815
UniSTS entry: Chr 22 RH27829
UniSTS entry: (n/a)
UniSTS entry: (n/a)
UniSTS entry: RH70737
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_002309.3 Homo sapiens leukemia inhibitory factor (cholinergic differentiation factor) (LIF), mRNA PA
BC069540.1 Homo sapiens leukemia inhibitory factor (cholinergic differentiation factor), mRNA (cDNA clone MGC:97016 IMAGE:7262225), complete cds P
BC093733.1 Homo sapiens leukemia inhibitory factor (cholinergic differentiation factor), mRNA (cDNA clone MGC:120768 IMAGE:7939578), complete cds P
BC093735.1 Homo sapiens leukemia inhibitory factor (cholinergic differentiation factor), mRNA (cDNA clone MGC:120770 IMAGE:7939580), complete cds P
X13967.1 Human mRNA for leukaemia inhibitory factor (LIF/HILDA) P
AK315310.1 Homo sapiens cDNA, FLJ96342, Homo sapiens leukemia inhibitory factor (cholinergicdifferentiation factor) (LIF), mRNA P
BC143305.1 Homo sapiens cDNA clone IMAGE:9051810 P

EST sequences (10 of 84) [Show all sequences]

AI147138.1 Clone IMAGE:1509724 mixed 3' read
BX099968.1 Clone IMAGp998N02238_;_IMAGE:153025 mammary gland
AI203060.1 Clone IMAGE:1942528 uncharacterized tissue 3' read A
AI287298.1 Clone IMAGE:1986002 uterus 3' read A
CB216985.1 Clone IMAGE:5938518 uterus 5' read
CB217076.1 Clone IMAGE:5938519 uterus 5' read
R50018.1 Clone IMAGE:153025 mammary gland 5' read
R50354.1 Clone IMAGE:153025 mammary gland 3' read
AI493227.1 Clone IMAGE:2131961 stomach 3' read A
AI796373.1 Clone IMAGE:2403054 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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